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. 1974 Apr 6;2(5909):11–14. doi: 10.1136/bmj.2.5909.11

Renal Lesions of Subacute Infective Endocarditis

J M Boulton-Jones, J G P Sissons, D J Evans, D K Peters
PMCID: PMC1610141  PMID: 4595180

Abstract

This paper gives an account of five patients with glomerulonephritis complicating subacute infective endocarditis. In three patients with focal (segmental) glomerulonephritis granular deposits of immunoglobulin and C3 and reduced serum complement suggested an immune-complex aetiology; but in two patients with a diffuse proliferative glomerulonephritis no Ig or C3 was detected in the diseased glomeruli and the pathogenetic mechanism remained undetermined. Four of the five patients developed renal failure needing dialysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berman L., Meyers A. M., Abrahams C. Glomerulonephritis, nephrotic syndrome and bacterial endocarditis. S Afr Med J. 1972 Jun 17;46(25):850–851. [PubMed] [Google Scholar]
  2. Burch G. E., Colcolough H. L. Progressive Coxsackie viral pancarditis and nephritis. Ann Intern Med. 1969 Nov;71(5):963–970. doi: 10.7326/0003-4819-71-5-963. [DOI] [PubMed] [Google Scholar]
  3. Feltkamp T. E., Boode J. H. Elution of antibodies from biopsy tissue. J Clin Pathol. 1970 Oct;23(7):629–631. doi: 10.1136/jcp.23.7.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Germuth F. G., Jr, Senterfit L. B., Dreesman G. R. Immune complex disease. V. The nature of the circulating complexes associated with glomerular alterations in the chronic BSA-rabbit system. Johns Hopkins Med J. 1972 Jun;130(6):344–357. [PubMed] [Google Scholar]
  5. Gutman R. A., Striker G. E., Gilliland B. C., Cutler R. E. The immune complex glomerulonephritis of bacterial endocarditis. Medicine (Baltimore) 1972 Jan;51(1):1–25. doi: 10.1097/00005792-197201000-00001. [DOI] [PubMed] [Google Scholar]
  6. Levy R. L., Hong R. The immune nature of subacute bacterial endocarditis (SBE) nephritis. Am J Med. 1973 May;54(5):645–652. doi: 10.1016/0002-9343(73)90123-x. [DOI] [PubMed] [Google Scholar]
  7. Macanovic M., Evans D. J., Peters D. K. Alllergic response to glomerular basement membrane in patients with glomerulonephritis. Lancet. 1972 Jul 29;2(7770):207–210. doi: 10.1016/s0140-6736(72)91637-6. [DOI] [PubMed] [Google Scholar]
  8. Morel-Maroger L., Sraer J. D., Herreman G., Godeau P. Kidney in subacute endocarditis. Pathological and immunofluorescence findings. Arch Pathol. 1972 Sep;94(3):205–213. [PubMed] [Google Scholar]
  9. Tu W. H., Shearn M. A., Lee J. C. Acute diffuse glomerulonephritis in acute staphylococcal endocarditis. Ann Intern Med. 1969 Aug;71(2):335–341. doi: 10.7326/0003-4819-71-2-335. [DOI] [PubMed] [Google Scholar]
  10. Williams D. G., Lachmann P. J., Charlesworth J. A., Peters D. K. Role of C3b in the breakdown of C3 in hypocomplementaemic mesangiocapillary glomerulonephritis. Lancet. 1973 Mar 3;1(7801):447–449. doi: 10.1016/s0140-6736(73)91877-1. [DOI] [PubMed] [Google Scholar]
  11. Wilson C. B., Dixon F. J. Quantitation of acute and chronic serum sickness in the rabbit. J Exp Med. 1971 Sep 1;134(3 Pt 2):7s–8s. [PubMed] [Google Scholar]

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