Abstract
The frequency of rosette-forming thymus-dependent lymphocytes was reduced in the peripheral blood of malnourished infants and children. The reduced frequency parallelled the impairment of delayed hypersensitivity response to 2, 4-dinitrochlorobenzene and decreased DNA synthesis by lymphocytes challenged with phytohaemagglutinin. The abnormalities were reversed on nutritional improvement.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Antia A. U., McFarlane H., Soothill J. F. Serum siderophilin in kwashiorkor. Arch Dis Child. 1968 Aug;43(230):459–462. doi: 10.1136/adc.43.230.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chandra R. K. Immunocompetence in undernutrition. J Pediatr. 1972 Dec;81(6):1194–1200. doi: 10.1016/s0022-3476(72)80262-2. [DOI] [PubMed] [Google Scholar]
- Jondal M., Holm G., Wigzell H. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. J Exp Med. 1972 Aug 1;136(2):207–215. doi: 10.1084/jem.136.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sellmeyer E., Bhettay E., Truswell A. S., Meyers O. L., Hansen J. D. Lymphocyte transformation in malnourished children. Arch Dis Child. 1972 Jun;47(253):429–435. doi: 10.1136/adc.47.253.429. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Seth V., Chandra R. K. Opsonic activity, phagocytosis, and bactericidal capacity of polymorphs in undernutrition. Arch Dis Child. 1972 Apr;47(252):282–284. doi: 10.1136/adc.47.252.282. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sirisinha S., Edelman R., Suskind R., Charupatana C., Olson R. E. Complement and C3-proactivator levels in children with protein-calorie malnutrition and effect of dietary treatment. Lancet. 1973 May 12;1(7811):1016–1020. doi: 10.1016/s0140-6736(73)90663-6. [DOI] [PubMed] [Google Scholar]
- Smythe P. M., Brereton-Stiles G. G., Grace H. J., Mafoyane A., Schonland M., Coovadia H. M., Loening W. E., Parent M. A., Vos G. H. Thymolymphatic deficiency and depression of cell-mediated immunity in protein-calorie malnutrition. Lancet. 1971 Oct 30;2(7731):939–943. doi: 10.1016/s0140-6736(71)90267-4. [DOI] [PubMed] [Google Scholar]
- Wybran J., Fudenberg H. H. Thymus-derived rosette-forming cells in various human disease states: cancer, lymphoma, bacterial and viral infections, and other diseases. J Clin Invest. 1973 May;52(5):1026–1032. doi: 10.1172/JCI107267. [DOI] [PMC free article] [PubMed] [Google Scholar]