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. 1974 Sep 14;3(5932):647–650. doi: 10.1136/bmj.3.5932.647

Vitamin D and Myocardial Infarction

Victor Lindén
PMCID: PMC1611643  PMID: 4425790

Abstract

A detailed investigation was carried out into the consumption of vitamin D from different sources in patients who had suffered from myocardial infarction, angina pectoris, and degenerative joint diseases. Randomly selected controls of the same ages and sex were drawn from the Central Bureau of Statistics. The consumption was significantly higher in infarction patients. A daily intake of 30 μg may be the critical level. Student's t test for trend showed increasing probability of myocardial infarction with increasing intake of vitamin D, and more infarction patients than controls had a history of kidney stone. Long-term high consumption of vitamin D may be a precipitating cause of myocardial infarction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dalderup L. M. Ischaemic heart-disease and vitamin D. Lancet. 1973 Jul 14;2(7820):92–92. doi: 10.1016/s0140-6736(73)93282-0. [DOI] [PubMed] [Google Scholar]
  2. Dalderup L. M., Stockmann V. A., Rechsteiner De Vos H., van der Slikke G. J. Survey on coronary heart disease in relation to diet in physically active farmers. Voeding. 1965 May 15;26(5):245–275. [PubMed] [Google Scholar]
  3. Dale A. E., Lowenberg M. E. Consumption of vitamin D in fortified and natural foods and in vitamin preparations. J Pediatr. 1967 Jun;70(6):952–955. doi: 10.1016/s0022-3476(67)80268-3. [DOI] [PubMed] [Google Scholar]
  4. FEENSTRA L., WILKENS J. H. CHOLESTEROL EN VITAMINE D. Ned Tijdschr Geneeskd. 1965 Mar 27;109:615–619. [PubMed] [Google Scholar]
  5. FELLERS F. X., SCHWARTZ R. Etiology of the severe form of idiopathic hypercalcemia of infancy; a defect in vitamin D metabolism. N Engl J Med. 1958 Nov 27;259(22):1050–1058. doi: 10.1056/NEJM195811272592202. [DOI] [PubMed] [Google Scholar]
  6. GLOVER M., GLOVER J., MORTON R. A. Provitamin D3 in tissues and the conversion of cholesterol to 7-dehydrocholesterol in vivo. Biochem J. 1952 Apr;51(1):1–9. doi: 10.1042/bj0510001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. KINLEY L. J., KRAUSE R. F. Influence of vitamin A on cholesterol blood levels. Proc Soc Exp Biol Med. 1959 Nov;102:353–355. doi: 10.3181/00379727-102-25245. [DOI] [PubMed] [Google Scholar]
  8. Kaserer H. P., Bibitz H. J., Witontky O. Uber eine tödliche Vitamin-D-Intoxikation beim Erwachsenen. Wien Klin Wochenschr. 1966 Jun 24;78(25):463–465. [PubMed] [Google Scholar]
  9. Knox E. G. Ischaemic-heart-disease mortality and dietary intake of calcium. Lancet. 1973 Jun 30;1(7818):1465–1467. doi: 10.1016/s0140-6736(73)91808-4. [DOI] [PubMed] [Google Scholar]
  10. LOWE K. G., HENDERSON J. L., PARK W. W., McGREAL D. A. The idiopathic hypercalcaemic syndromes of infancy. Lancet. 1954 Jul 17;267(6829):101–110. doi: 10.1016/s0140-6736(54)90093-8. [DOI] [PubMed] [Google Scholar]
  11. Linden V. Myocardial infarction and urolithiasis. A preliminary communication. J Kans Med Soc. 1972 Dec;73(12):503–505. [PubMed] [Google Scholar]
  12. Loomis W. F. Skin-pigment regulation of vitamin-D biosynthesis in man. Science. 1967 Aug 4;157(3788):501–506. doi: 10.1126/science.157.3788.501. [DOI] [PubMed] [Google Scholar]
  13. ROSS F. C., CAMPBELL A. H. The effect of vitamin A and vitamin D capsules upon the incidence of coronary heart disease and blood cholesterol. Med J Aust. 1961 Aug 19;48(2):307–311. doi: 10.5694/j.1326-5377.1961.tb69522.x. [DOI] [PubMed] [Google Scholar]
  14. SMITH D. W., BLIZZARD R. M., HARRISON H. E. Idiopathic hypercalcemia; a case report with assays of vitamin D in the serum. Pediatrics. 1959 Aug;24(2):258–269. [PubMed] [Google Scholar]
  15. Seelig M. S. Vitamin D and cardiovascular, renal, and brain damage in infancy and childhood. Ann N Y Acad Sci. 1969 Sep 26;147(15):539–582. doi: 10.1111/j.1749-6632.1967.tb41272.x. [DOI] [PubMed] [Google Scholar]
  16. Westlund K. Urolithiasis and coronary heart disease: a note on association. Am J Epidemiol. 1973 Mar;97(3):167–172. doi: 10.1093/oxfordjournals.aje.a121497. [DOI] [PubMed] [Google Scholar]
  17. Witkop C. J., Jr Genetics and nutrition. Fed Proc. 1967 Jan-Feb;26(1):148–151. [PubMed] [Google Scholar]
  18. YACOWITZ H., FLEISCHMAN A. I., BIERENBAUM M. L. EFFECTS OF ORAL CALCIUM UPON SERUM LIPIDS IN MAN. Br Med J. 1965 May 22;1(5446):1352–1354. doi: 10.1136/bmj.1.5446.1352. [DOI] [PMC free article] [PubMed] [Google Scholar]

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