Abstract
A new unstable haemoglobin, α2β215 Trp→ Arg (Hb Belfast), with increased oxygen affinity has been found during the routine investigation of a long-stay psychiatric patient. It seemed to cause little haematological disorder. The reticulocytes synthesized normal and abnormal β-chains at the same rate but in the circulating blood Hb Belfast amounted to only 27·5% of the total haemoglobin.
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