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. 1960 Oct;152(4):559–567. doi: 10.1097/00000658-196010000-00001

Effects of Chemotherapeutic Agents on Wounds Contaminated with Tumor Cells: An Experimental Study*

Imran Hatiboglu, George E Moore, Hans J Wilkens, Ferdinand Hoffmeister
PMCID: PMC1613791  PMID: 13712247

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ACKERMAN L. V., WHEAT M. W., Jr The implantation of cancer; an avoidable surgical risk. Surgery. 1955 Mar;37(3):341–355. [PubMed] [Google Scholar]
  2. BLIXENKRONE-MOLLER N. Mitomen chemotherapy given in relation to operation for cancer of the abdominal organs. Acta Chir Scand. 1959 Jul 30;117:189–196. [PubMed] [Google Scholar]
  3. BOREHAM P. The surgical spread of cancer in urology. Br J Urol. 1956 Jun;28(2):163–175. doi: 10.1111/j.1464-410x.1956.tb04752.x. [DOI] [PubMed] [Google Scholar]
  4. BOREHAM P. [Implantation metastases from cancer of the large bowel]. Br J Surg. 1958 Sep;46(196):103–108. doi: 10.1002/bjs.18004619603. [DOI] [PubMed] [Google Scholar]
  5. COLE W. H., PACKARD D., SOUTHWICK H. W. Carcinoma of the colon with special reference to prevention of recurrence. J Am Med Assoc. 1954 Aug 28;155(18):1549–1553. doi: 10.1001/jama.1954.03690360001001. [DOI] [PubMed] [Google Scholar]
  6. COLE W. H. Recurrence in carcinoma of the colon and proximal rectum following resection for carcinoma. AMA Arch Surg. 1952 Aug;65(2):264–270. doi: 10.1001/archsurg.1952.01260020277008. [DOI] [PubMed] [Google Scholar]
  7. COLLIER R. G., EY R. C., McDONALD G. O., COLE W. H. Wound irrigation to prevent local recurrence of cancer. AMA Arch Surg. 1959 Apr;78(4):528–534. doi: 10.1001/archsurg.1959.04320040024008. [DOI] [PubMed] [Google Scholar]
  8. ECONOMOU S. G., MRAZEK R., McDONALD G., SLAUGHTER D., COLE W. H. The intraperitoneal use of nitrogen mustard at the time of operation for cancer. Ann N Y Acad Sci. 1958 Apr 24;68(3):1097–1102. doi: 10.1111/j.1749-6632.1958.tb42669.x. [DOI] [PubMed] [Google Scholar]
  9. FLEISCHNER F. G., BERENBERG A. L. Recurrent carcinoma of the colon at the site of the anastomosis. Roentgen observations. Radiology. 1956 Apr;66(4):540–547. doi: 10.1148/66.4.540. [DOI] [PubMed] [Google Scholar]
  10. GLIEDMAN M. L., GRANT R. N., VESTAL B. L., ROGERS C. E., KARLSON K. E. Clorpactin, a surgical adjunct; antimicrobial and tumorcidal action. Surg Forum. 1957;8:104–108. [PubMed] [Google Scholar]
  11. GOLIGHER J. C., DUKES C. E., BUSSEY H. J. R. Local recurrences after sphincter saving excisions for carcinoma of the rectum and rectosigmoid. Br J Surg. 1951 Nov;39(155):199–211. doi: 10.1002/bjs.18003915504. [DOI] [PubMed] [Google Scholar]
  12. GUISS R. L. The implantation of cancer cells within a fistula in ano: case report. Surgery. 1954 Jul;36(1):136–139. [PubMed] [Google Scholar]
  13. Haagensen C. D., Stout A. P. CARCINOMA OF THE BREAST-PART I; RESULTS OF TREATMENT. Ann Surg. 1942 Dec;116(6):801–815. doi: 10.1097/00000658-194212000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. KETCHAM A. S. The use of a hypochlorous acid derivative in the control of cancer: an animal investigation of seeded wounds. Cancer. 1960 Jan-Feb;13:20–24. doi: 10.1002/1097-0142(196001/02)13:1<20::aid-cncr2820130105>3.0.co;2-0. [DOI] [PubMed] [Google Scholar]
  15. KONDO T., TSUKUI K. Effects of nitrogen mustard N-oxide, x-rays, and cortisone on Yoshida sarcoma metastasis development. Proc Soc Exp Biol Med. 1959 Nov;102:384–386. doi: 10.3181/00379727-102-25258. [DOI] [PubMed] [Google Scholar]
  16. LASZLO J., BURK D., WIGHT K. Inhibition and enhancement effects of hypochlorite on ascites tumor cell metabolism and growth, and on host resistance. J Natl Cancer Inst. 1959 Sep;23:351–365. [PubMed] [Google Scholar]
  17. MCDONALD G. O., LIVINGSTON C., BOYLES C. F., COLE W. H. The prophylactic treatment of malignant disease with nitrogen mustard and triethylenethiophosphoramide (thio-TEPA). Ann Surg. 1957 May;145(5):624–629. doi: 10.1097/00000658-195705000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. MOORE G. E., KONDO T. Study of adjuvant cancer chemotherapy by model experiments. Surgery. 1958 Jul;44(1):199–200. [PubMed] [Google Scholar]
  19. MOORE G. E., SAKO K. The spread of carcinoma of the colon and rectum: a study of invasion of blood vessels, lymph nodes and the peritoneum by tumors cells. Dis Colon Rectum. 1959 Jan-Feb;2(1):92–97. doi: 10.1007/BF02616625. [DOI] [PubMed] [Google Scholar]
  20. MORGAN C. N. Discussion on major surgery in carcinoma of the rectum with or without colostomy, excluding the anal canal & including the rectosigmoid: restorative resection. Proc R Soc Med. 1957 Dec;50(12):1050–1052. [PubMed] [Google Scholar]
  21. McCLURE J. H., MENGERT W. F. Experiences with intra-abdominal nitrogen mustard; a report on eleven women with pelvic malignancy. Am J Obstet Gynecol. 1959 Mar;77(3):676–678. doi: 10.1016/s0002-9378(16)36741-2. [DOI] [PubMed] [Google Scholar]
  22. SHIMKIN M. B., MOORE G. E. Adjuvant use of chemotherapy in the surgical treatment of cancer; plan of cooperative study. J Am Med Assoc. 1958 Aug 2;167(14):1710–1714. doi: 10.1001/jama.1958.02990310016003. [DOI] [PubMed] [Google Scholar]
  23. SHIP A. G., ECK R. V., SMITH R. R. Local chemotherapy of experimentally tumor-seeded wounds. Cancer. 1958 Jul-Aug;11(4):687–695. doi: 10.1002/1097-0142(195807/08)11:4<687::aid-cncr2820110403>3.0.co;2-b. [DOI] [PubMed] [Google Scholar]
  24. SMITH R. R., GEHAN E. A. Effect of formaldehyde wound wash on development of local wound recurrences. J Natl Cancer Inst. 1959 Dec;23:1339–1345. [PubMed] [Google Scholar]
  25. SMITH R. R., THOMAS L. B., HILBERG A. W. Cancer cell contamination of operative wounds. Cancer. 1958 Jan-Feb;11(1):53–62. doi: 10.1002/1097-0142(195801/02)11:1<53::aid-cncr2820110113>3.0.co;2-x. [DOI] [PubMed] [Google Scholar]

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