Abstract
OBJECTIVES. This study examined the association of smoking status and pack-years of smoking with facial wrinkling in men and women. METHODS. We conducted a cross-sectional study of 299 never smokers, 551 former smokers and 286 current smokers, aged 30 through 69 years, drawn from a health maintenance organization. Smoking status, pack-years of smoking, and potential confounding variables were assessed by questionnaire. Facial wrinkle category, a dichotomous variable, and facial wrinkle score, a computed continuous variable, were assessed by blinded standardized visual assessment. Wrinkling was so uncommon among 30- through 39-year-old subjects that analyses were restricted to subjects aged 40 and over (227 never smokers, 456 former smokers, and 228 current smokers). RESULTS. With age, average sun exposure, and body mass index controlled, the estimated relative risk of moderate/severe wrinkling for current smokers compared to never smokers was 2.3 (95% confidence interval [CI] = 1.2, 4.2) among men and 3.1 (95% CI = 1.6, 5.9) among women. Pack-years was positively associated with facial wrinkle score in women aged 40 through 69 years and in men aged 40 through 59 years. In both groups, the increased risk of wrinkling was equivalent to about 1.4 years of aging. CONCLUSIONS. Our results support earlier findings that risk of facial wrinkling is greater in cigarette smokers than in never smokers.
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Selected References
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- Daniell H. W. Smoker's wrinkles. A study in the epidemiology of "crow's feet". Ann Intern Med. 1971 Dec;75(6):873–880. doi: 10.7326/0003-4819-75-6-873. [DOI] [PubMed] [Google Scholar]
- Kadunce D. P., Burr R., Gress R., Kanner R., Lyon J. L., Zone J. J. Cigarette smoking: risk factor for premature facial wrinkling. Ann Intern Med. 1991 May 15;114(10):840–844. doi: 10.7326/0003-4819-114-10-840. [DOI] [PubMed] [Google Scholar]
- McGinnis J. M., Foege W. H. Actual causes of death in the United States. JAMA. 1993 Nov 10;270(18):2207–2212. [PubMed] [Google Scholar]
- Model D. Smoker's face: an underrated clinical sign? Br Med J (Clin Res Ed) 1985 Dec 21;291(6511):1760–1762. doi: 10.1136/bmj.291.6511.1760. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reus W. F., Robson M. C., Zachary L., Heggers J. P. Acute effects of tobacco smoking on blood flow in the cutaneous micro-circulation. Br J Plast Surg. 1984 Apr;37(2):213–215. doi: 10.1016/0007-1226(84)90011-0. [DOI] [PubMed] [Google Scholar]
- Richardson D. Effects of tobacco smoke inhalation on capillary blood flow in human skin. Arch Environ Health. 1987 Jan-Feb;42(1):19–25. doi: 10.1080/00039896.1987.9935790. [DOI] [PubMed] [Google Scholar]