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. 1995 Mar;39(3):771–774. doi: 10.1128/AAC.39.3.771

Identification of a carbenicillin-hydrolyzing beta-lactamase in Alcaligenes denitrificans subsp. xylosoxydans.

D Decré 1, G Arlet 1, E Bergogne-Bérézin 1, A Philippon 1
PMCID: PMC162624  PMID: 7793891

Abstract

Eleven strains of Alcaligenes denitrificans subsp. xylosoxydans produced a beta-lactamase with a pI of 5.7 with kinetic data characteristic of a PSE-1-type enzyme. A CARB-type enzyme was identified by using an intragenic DNA probe of blaCARB. Hybridization of genomic DNA after XbaI restriction and pulsed-field electrophoresis suggested a chromosomal location for the gene.

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Selected References

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