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. 1995 Apr;39(4):990–995. doi: 10.1128/aac.39.4.990

Comparative in vitro activities of L-695,256, a novel carbapenem, against gram-positive bacteria.

G Malanoski 1, L Collins 1, C T Eliopoulos 1, R C Moellering Jr 1, G M Eliopoulos 1
PMCID: PMC162669  PMID: 7786011

Abstract

The in vitro activity of a prototype 2-aryl carbapenem, L-695,256, against gram-positive bacteria was examined. All streptococci and oxacillin-susceptible and -resistant staphylococci were inhibited at concentrations of < or = 0.125, < or = 0.125, and 4 micrograms/ml, respectively. The activity of L-695,256 was superior to that of imipenem against other organisms intrinsically resistant to beta-lactams.

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Selected References

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