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. 1980 Jul;55(7):532–536. doi: 10.1136/adc.55.7.532

Renal transplantation in children less than 5 years of age.

G Rizzoni, M H Malekzadeh, A J Pennisi, R B Ettenger, C H Uittenbogaart, R N Fine
PMCID: PMC1626782  PMID: 7002060

Abstract

19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors was 26 +/- 11%. 10 children are currently surviving with functioning allographs (7 cadavers and 3 live relatives); 4 have died and 5 are undergoing dialysis after the loss of at least one allograft. Despite the poor allograft survival rate the fact that 7 children are surviving with cadaver allografts indicates that the lack of a living related donor should not prevent transplants in young children.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Belzer F. O., Schweitzer R. T., Holliday M., Kountz S. L. Renal homotransplantation in children. Am J Surg. 1972 Aug;124(2):270–278. doi: 10.1016/0002-9610(72)90024-4. [DOI] [PubMed] [Google Scholar]
  2. Cameron J. S., Turner D. R. Recurrent glomerulonephritis in allografted kidneys. Clin Nephrol. 1977 Feb;7(2):47–54. [PubMed] [Google Scholar]
  3. Cerilli G. J., Nelsen C., Dorfmann L. Renal homotransplantation in infants and children with the hemolytic-uremic syndrome. Surgery. 1972 Jan;71(1):66–71. [PubMed] [Google Scholar]
  4. Dausset J., Hors J., Busson M., Festenstein H., Oliver R. T., Paris A. M., Sachs J. A. Serologically defined HL-A antigens and long-term survival of cadaver kidney transplants. A joint analysis of 918 cases performed by France-Transplant and the London Transplant Group. N Engl J Med. 1974 May 2;290(18):979–984. doi: 10.1056/NEJM197405022901801. [DOI] [PubMed] [Google Scholar]
  5. Fine R. N., De Palma J. R., Lieberman E., Donnell G. N., Gordon A., Maxwell M. H. Extended hemodialysis in children with chronic renal failure. J Pediatr. 1968 Nov;73(5):706–713. doi: 10.1016/s0022-3476(68)80176-3. [DOI] [PubMed] [Google Scholar]
  6. Fine R. N., Edelbrock H. H., Riddell H., Malekzadeh M. H., Pennisi A. J., Ettenger R. B., Uittenbogaart C. H., Korsch B. M. Renal transplantation in children. Urology. 1977 Jun;9(6 Suppl):61–71. doi: 10.1080/21548331.1974.11707964. [DOI] [PubMed] [Google Scholar]
  7. Hodson E. M., Najarian J. S., Kjellstrand C. M., Simmons R. L., Mauer S. M. Renal transplantation in children ages 1 to 5 years. Pediatrics. 1978 Mar;61(3):458–464. doi: 10.1542/peds.61.3.458. [DOI] [PubMed] [Google Scholar]
  8. Jervell J., Dahl B. O., Jakobsen A., Lund P. K., Thayssen P., Fjeldborg O., Hansen H. E., Koch B., Lindstrøm B., Larson O. Renal transplantation in insulin-treated diabetics. Transplant Proc. 1979 Mar;11(1):60–62. [PubMed] [Google Scholar]
  9. Kwun Y. A., Butt K. M., Kim K. H., Kountz S. L., Moel D. I. Successful renal transplantation in a 3-month-old infant. J Pediatr. 1978 Mar;92(3):426–429. doi: 10.1016/s0022-3476(78)80435-1. [DOI] [PubMed] [Google Scholar]
  10. LaPlante M. P., Kaufman J. J., Goldman R., Gonick H. C., Martin D. C., Goodwin W. E. Kidney transplantation in children. Pediatrics. 1970 Nov;46(5):665–677. [PubMed] [Google Scholar]
  11. Lawson R. K., Talwalkar Y. B., Musgrave J. E., Campbell R. A., Hodges C. V. Renal transplantation in pediatric patients. J Urol. 1975 Feb;113(2):225–229. doi: 10.1016/s0022-5347(17)59450-1. [DOI] [PubMed] [Google Scholar]
  12. Malekzadeh M. H., Heuser E. T., Ettenger R. B., Pennisi A. J., Uittenbogaart C. H., Warshaw B. L., Fine R. N. Focal glomerulosclerosis and renal transplantation. J Pediatr. 1979 Aug;95(2):249–254. doi: 10.1016/s0022-3476(79)80660-5. [DOI] [PubMed] [Google Scholar]
  13. Martin L. W., Gonzalez L. L., West C. D., Spitzer R., Reyes P. M., Moore C. C. Clinical problems encountered in renal homotransplantation in children. J Pediatr Surg. 1970 Apr;5(2):207–214. doi: 10.1016/0022-3468(70)90277-0. [DOI] [PubMed] [Google Scholar]
  14. Najarian J. S., Simmons R. L., Tallent M. B., Kiellstrand C. M., Buselmeier T. J., Vernier R. L., Michael A. F. Renal transplantation in infants and children. Ann Surg. 1971 Oct;174(4):583–601. doi: 10.1097/00000658-197110000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Opelz G., Sengar D. P., Mickey M. R., Terasaki P. I. Effect of blood transfusions on subsequent kidney transplants. Transplant Proc. 1973 Mar;5(1):253–259. [PubMed] [Google Scholar]
  16. Pennisi A. J., Costin G., Phillips L. S., Uittenbogaart C., Ettenger R. B., Malekzadeh M. H., Fine R. N. Linear growth in long-term renal allograft recipients. Clin Nephrol. 1977 Oct;8(4):415–421. [PubMed] [Google Scholar]
  17. Terasaki P. I., Kreisler M., Mickey R. M. Presensitization and kidney transplant failures. Postgrad Med J. 1971 Feb;47(544):89–100. [PMC free article] [PubMed] [Google Scholar]
  18. Uittenbogaart C. H., Robinson B. J., Malekzadeh M. H., Pennisi A. J., Ettenger R. B., Fine R. N. Use of antithymocyte globulin (dose by rosette protocol) in pediatric renal allograft recipients. Transplantation. 1979 Oct;28(4):291–293. doi: 10.1097/00007890-197910000-00005. [DOI] [PubMed] [Google Scholar]

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