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. 1980 Apr;55(4):259–264. doi: 10.1136/adc.55.4.259

Follow-up of children of diabetic mothers.

M Cummins, M Norrish
PMCID: PMC1626811  PMID: 7416774

Abstract

The results of a follow-up study of infants of diabetic mothers are presented. The antenatal care of all such mothers was supervised in a combined clinic by obstetricians and physicians, and good diabetic control was achieved in most of them. 51 mothers delivered 73 infants, all liveborn, between the years 1964 and 1972 inclusive at Hammersmith Hospital. There were no fetal deaths. 66 infants survived the neonatal period, and 63 the first 2 years of life. 51 children, including all those seriously ill in the neonatal period, could be traced. Detailed neurological and general examinations including skinfold measurements were made, and the IQ measured. Four children were found to have major handicaps. These were severe deafness, epilepsy, low IQ, and myopia. No other neurological abnormalities were detected, and the distribution of full-scale IQs was normal. The distribution of height and head circumference centiles was near normal, but an increased number of children had weights above the 90th centile. No significant congenital malformations were found in these 51 survivors, and none has so far developed diabetes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amendt P., Michaelis D., Hildmann W. Clinical and metabolic studies in children of diabetic-mothers. Endokrinologie. 1976 Jul;67(3):351–361. [PubMed] [Google Scholar]
  2. Breidahl H. D. The growth and development of children born to mothers with diabetes. Med J Aust. 1966 Feb 12;1(7):268–270. doi: 10.5694/j.1326-5377.1966.tb19702.x. [DOI] [PubMed] [Google Scholar]
  3. Brudenell J. M. Delivering the baby of the diabetic mother. J R Soc Med. 1978 Mar;71(3):207–211. doi: 10.1177/014107687807100312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cassar J., Gordon H., Dixon H. G., Cummins M., Joplin G. F. Simplified management of pregnancy complicated by diabetes. Br J Obstet Gynaecol. 1978 Aug;85(8):585–591. doi: 10.1111/j.1471-0528.1978.tb14925.x. [DOI] [PubMed] [Google Scholar]
  5. Churchill J. A., Berendes H. W., Nemore J. Neuropsychological deficits in children of diabetic mothers. A report from the Collaborative Sdy of Cerebral Palsy. Am J Obstet Gynecol. 1969 Sep 15;105(2):257–268. doi: 10.1016/0002-9378(69)90067-2. [DOI] [PubMed] [Google Scholar]
  6. FELD J. G. Two types of tables for use with Wechsler's intelligence scales. J Clin Psychol. 1960 Jan;16:3–7. doi: 10.1002/1097-4679(196001)16:1<3::aid-jclp2270160102>3.0.co;2-9. [DOI] [PubMed] [Google Scholar]
  7. Farquhar J. W. Prognosis for babies born to diabetic mothers in Edinburgh. Arch Dis Child. 1969 Feb;44(233):36–47. doi: 10.1136/adc.44.233.36. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. François R., Picaud J. J., Ruitton-Ugliengo A., David L., Cartal M. J., Bauer D. The newborn of diabetic mothers. Observations on 154 cases, 1958-1972. Biol Neonate. 1974;24(1):1–31. doi: 10.1159/000240628. [DOI] [PubMed] [Google Scholar]
  9. Gamsu H. R. Neonatal morbidity in infants of diabetic mothers. J R Soc Med. 1978 Mar;71(3):211–222. doi: 10.1177/014107687807100313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gruenwald P. Growth of the human fetus. I. Normal growth and its variation. Am J Obstet Gynecol. 1966 Apr 15;94(8):1112–1119. doi: 10.1016/0002-9378(66)90774-5. [DOI] [PubMed] [Google Scholar]
  11. HAGBARD L., OLOW I., REINAND T. A follow-up study of 514 children of diabetic mothers. Acta Paediatr. 1959 Mar;48(2):184–197. [PubMed] [Google Scholar]
  12. Haworth J. C., McRae K. N., Dilling L. A. Prognosis of infants of diabetic mothers in relation to neonatal hypoglycaemia. Dev Med Child Neurol. 1976 Aug;18(4):471–479. doi: 10.1111/j.1469-8749.1976.tb03686.x. [DOI] [PubMed] [Google Scholar]
  13. Kemball M. L., McIver C., Milner R. D., Nourse C. H., Schiff D., Tiernan J. R. Neonatal hypoglycaemia in infants of diabetic mothers given sulphonylurea drugs in pregnancy. Arch Dis Child. 1970 Oct;45(243):696–701. doi: 10.1136/adc.45.243.696. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Sheridan M. D. The development of vision, hearing and communication in babies and young children. Proc R Soc Med. 1969 Oct;62(10):999–1004. [PMC free article] [PubMed] [Google Scholar]
  15. Stehbens J. A., Baker G. L., Kitchell M. Outcome at ages 1, 3, and 5 years of children born to diabetic women. Am J Obstet Gynecol. 1977 Feb 15;127(4):408–413. doi: 10.1016/0002-9378(77)90499-9. [DOI] [PubMed] [Google Scholar]
  16. TANNER J. M., WHITEHOUSE R. H. Standards for subcutaneous fat in British children. Percentiles for thickness of skinfolds over triceps and below scapula. Br Med J. 1962 Feb 17;1(5276):446–450. doi: 10.1136/bmj.1.5276.446. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Tanner J. M., Whitehouse R. H., Takaishi M. Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. II. Arch Dis Child. 1966 Dec;41(220):613–635. doi: 10.1136/adc.41.220.613. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Verdy M., Gagnon M. A., Caron D. Letter: Birth weight and adult obesity in children of diabetic mothers. N Engl J Med. 1974 Mar 7;290(10):576–576. doi: 10.1056/nejm197403072901025. [DOI] [PubMed] [Google Scholar]
  19. WHITE P. Childhood diabetes. Its course, and influence on the second and third generations. Diabetes. 1960 Sep-Oct;9:345–355. doi: 10.2337/diab.9.5.345. [DOI] [PubMed] [Google Scholar]
  20. Weitz R., Laron Z. Height and weight of children born to mothers with diabetes mellitus. Isr J Med Sci. 1976 Mar;12(3):195–198. [PubMed] [Google Scholar]
  21. Whitelaw A. Subcutaneous fat in newborn infants of diabetic mothers: An indication of quality of diabetic control. Lancet. 1977 Jan 1;1(8001):15–18. doi: 10.1016/s0140-6736(77)91654-3. [DOI] [PubMed] [Google Scholar]
  22. Yssing M. Oestriol excretion in pregnant diabetics related to long-term prognosis of surviving children. Acta Endocrinol Suppl (Copenh) 1974 Jan;182:95–104. doi: 10.1530/acta.0.075s095. [DOI] [PubMed] [Google Scholar]

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