Abstract
The infantile spasms syndrome appeared on the same day in a pair of monozygotic twins at age 6 months. Clinical, electroencephalographic, and neuroradiological findings during the development of the disease are reported. One of the twins was treated with ACTH and in his case clinical and electroencephalographic improvement was more rapid than in the other who was treated with clonazepam. While the computer tomography scan initially showed in each twin an area of low density in the right fronto-parietal region, this had disappeared in the tomograms obtained about 8 months later.
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Selected References
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- Cao A., Cianchetti C., Signorini E., Loi M., Sanna G., De Virgiliis S. Agenesis of the corpus callosum, infantile spasms, spastic quadriplegia, microcephaly and severe mental retardation in three siblings. Clin Genet. 1977 Nov;12(5):290–296. doi: 10.1111/j.1399-0004.1977.tb00943.x. [DOI] [PubMed] [Google Scholar]
- Cotterittaud M. R., Delafin J. Présentation d'une observation familiale de maladie des spasmes en flexion avec hypsarythmia. Rev Neurol (Paris) 1965 Apr;112(4):301–303. [PubMed] [Google Scholar]
- Fleiszar K. A., Daniel W. L., Imrey P. B. Genetic study of infantile spasm with hypsarrhythmia. Epilepsia. 1977 Mar;18(1):55–62. doi: 10.1111/j.1528-1157.1977.tb05587.x. [DOI] [PubMed] [Google Scholar]
- Howitz P., Platz P. Infantile spasms and HLA antigens. Arch Dis Child. 1978 Aug;53(8):680–682. doi: 10.1136/adc.53.8.680. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lagenstein I., Willig R. P., Kühne D. Reversible cerebral atrophy caused by corticotrophin. Lancet. 1979 Jun 9;1(8128):1246–1247. doi: 10.1016/s0140-6736(79)91932-9. [DOI] [PubMed] [Google Scholar]
