Abstract
Life-threatening lingual haemorrhage was successfully treated in a 3-year-old haemophiliac who had a high level of inhibitor in his plasma. Repeated plasma exchange with high-dose factor VIII concentrate led to a cessation of bleeding. Immunosuppressive treatment introduced at the time of plasmapheresis and carried out for 6 weeks seems to have prevented the return of the inhibitor.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Allain J. P., Krieger G. R. Letter: Prothrombin-complex concentrate in treatment of classical haemophilia with factor-VIII antibody. Lancet. 1975 Dec 13;2(7946):1203–1203. doi: 10.1016/s0140-6736(75)92683-5. [DOI] [PubMed] [Google Scholar]
- Nilsson I. M., Hedner U. Immunosuppressive treatment in haemophiliacs with inhibitors to factor VIII and factor IX. Scand J Haematol. 1976 May;16(5):369–382. doi: 10.1111/j.1600-0609.1976.tb00330.x. [DOI] [PubMed] [Google Scholar]
- Stenbjerg S., Jorgensen J. Disseminated intravascular coagulation and infusion of factor-VIII-inhibitor bypassing activity. Lancet. 1977 Feb 12;1(8007):360–360. doi: 10.1016/s0140-6736(77)91156-4. [DOI] [PubMed] [Google Scholar]
