Skip to main content
PMC home page
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1981 Jan;56(1):40–44. doi: 10.1136/adc.56.1.40

Height and skeletal maturity in children with newly-diagnosed juvenile-onset diabetes.

A D Edelsten, I A Hughes, S Oakes, I R Gordon, D C Savage
PMCID: PMC1627077  PMID: 7469452

Abstract

Height and skeletal maturity scores (TW 2) were determined in 77 diabetic children at diagnosis and again in 48 of them after 1 to 4 years on insulin treatment. Boys, especially those of prepubertal age, were tall at onset. Girls had normal stature, but showed significant growth retardation after treatment. Skeletal maturity was appreciably advanced in both sexes at diagnosis, and on treatment returned to normal only in boys. Girls maintained their advanced skeletal maturity, resulting in an increased disparity between height and skeletal maturity. The results of this study suggest that a prediabetic metabolic abnormality may enhance skeletal maturity in children with diabetes and continues to operate in girls after treatment, despite a reduced growth rate.

Full text

PDF
40

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALLEN O. P. Symptoms suggesting prodromal stage of diabetes mellitus. Ohio State Med J. 1953 Mar;49(3):213–215. [PubMed] [Google Scholar]
  2. Baum J. D., Ounsted M., Smith M. A. Letter: Weight gain in infancy and subsequent development of diabetes mellitus in childhood. Lancet. 1975 Nov 1;2(7940):866–866. doi: 10.1016/s0140-6736(75)90250-0. [DOI] [PubMed] [Google Scholar]
  3. Birkbeck J. A. Growth in juvenile diabetes mellitus. Diabetologia. 1972 Jul;8(3):221–224. doi: 10.1007/BF01212266. [DOI] [PubMed] [Google Scholar]
  4. Craig J. O. Growth as a measurement of control in the management of diabetic children. Postgrad Med J. 1970 Sep;46(Suppl):607–610. [PubMed] [Google Scholar]
  5. Drayer N. M. Height of diabetic children at onset of symptoms. Arch Dis Child. 1974 Aug;49(8):616–620. doi: 10.1136/adc.49.8.616. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Evans N., Robinson V. P., Lister J. Growth and bone age of juvenile diabetics. Arch Dis Child. 1972 Aug;47(254):589–593. doi: 10.1136/adc.47.254.589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Fajans S. S., Floyd J. C., Tattersall R. B., Williamson J. R., Pek S., Taylor C. I. The various faces of diabetes in the young: changing concepts. Arch Intern Med. 1976 Feb;136(2):194–202. [PubMed] [Google Scholar]
  8. Hansen A. P., Johansen K. Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics. Diabetologia. 1970 Feb;6(1):27–33. doi: 10.1007/BF00425888. [DOI] [PubMed] [Google Scholar]
  9. Irvine W. J. Classification of idiopathic diabetes. Lancet. 1977 Mar 19;1(8012):638–642. doi: 10.1016/s0140-6736(77)92071-2. [DOI] [PubMed] [Google Scholar]
  10. Jivani S. K., Rayner P. H. Does control influence the growth of diabetic children? Arch Dis Child. 1973 Feb;48(2):109–115. doi: 10.1136/adc.48.2.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Pond H. Some aspects of growth in diabetic children. Postgrad Med J. 1970 Sep;46(Suppl):616–623. [PubMed] [Google Scholar]
  12. Steel J. M., Gray R. S., Clarke B. F. Obstetric history of diabetics: its relevance to the aetiology of diabetes. Br Med J. 1979 May 19;1(6174):1303–1305. doi: 10.1136/bmj.1.6174.1303. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Tanner J. M., Whitehouse R. H., Takaishi M. Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. II. Arch Dis Child. 1966 Dec;41(220):613–635. doi: 10.1136/adc.41.220.613. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Williams M. L., Savage D. C. Glycosylated haemoglobin levels in children with diabetes mellitus. Arch Dis Child. 1979 Apr;54(4):295–298. doi: 10.1136/adc.54.4.295. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES