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. 1981 Jul;56(7):525–529. doi: 10.1136/adc.56.7.525

Breast development in the newborn.

J F McKiernan, D Hull
PMCID: PMC1627340  PMID: 7271286

Abstract

Breast size and milk secretion was studied in term and preterm infants. Breast nodules were palpable in most of the mature infants, both boys and girls. In 6 term infants without palpable breast tissue there was a high incidence of complications during late pregnancy or delivery. In light-for-gestational age infants the breast diameter was generally appropriate for gestation. None of the infants under 31 weeks' gestation had palpable breast tissue at birth, but some in the first weeks of life developed breast tissue and secreted milk. Milk had been secreted by most of the mature infants by age 7 days, and the onset was earlier in light-for-dates infants. The breast does not regress rapidly after birth. The nodules persist into the second half of the first year by which time sex differences have emerged. Clearly the growth and activity of the neonatal breast cannot be explained solely in terms of the influence of maternal hormones towards the end of gestation. Further studies on early breast tissue development may indicate the other endocrine factors concerned.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BLUESTEIN D. D., WALL G. H. Persistent neonatal breast hypertrophy. Am J Dis Child. 1963 Mar;105:292–294. doi: 10.1001/archpedi.1963.02080040294012. [DOI] [PubMed] [Google Scholar]
  2. Capraro V. J., Dewhurst C. J. Breast disorders in childhood and adolescence. Clin Obstet Gynecol. 1975 Jun;18(2):25–50. doi: 10.1097/00003081-197506000-00003. [DOI] [PubMed] [Google Scholar]
  3. DOSSETT J. A. The nature of breast secretion in infancy. J Pathol Bacteriol. 1960 Jul;80:93–99. doi: 10.1002/path.1700800112. [DOI] [PubMed] [Google Scholar]
  4. Davies W. L., Moncrieff A. Composition of the milk from the breasts of newly-born infants. Biochem J. 1938 Jul;32(7):1238–1240. doi: 10.1042/bj0321238. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Farr V., Kerridge D. F., Mitchell R. G. The value of some external characteristics in the assessment of gestational age at birth. Dev Med Child Neurol. 1966 Dec;8(6):657–660. doi: 10.1111/j.1469-8749.1966.tb01823.x. [DOI] [PubMed] [Google Scholar]
  6. Frantz A. G. Prolactin. N Engl J Med. 1978 Jan 26;298(4):201–207. doi: 10.1056/NEJM197801262980408. [DOI] [PubMed] [Google Scholar]
  7. Guyda H. J., Friesen H. G. Serum prolactin levels in humans from birth to adult life. Pediatr Res. 1973 May;7(5):534–540. doi: 10.1203/00006450-197305000-00007. [DOI] [PubMed] [Google Scholar]
  8. KEITEL H. G., CHU E. BREAST NODULE IN PREMATURE INFANT. Am J Dis Child. 1965 Feb;109:121–122. doi: 10.1001/archpedi.1965.02090020123005. [DOI] [PubMed] [Google Scholar]
  9. Kulski J. K., Smith M., Hartmann P. E. Perinatal concentrations of progesterone, lactose and alpha-lactalbumin in the mammary secretion of women. J Endocrinol. 1977 Sep;74(3):509–510. doi: 10.1677/joe.0.0740509. [DOI] [PubMed] [Google Scholar]
  10. Nachtigall C. Verlaufsbeobachtungen über die physiologische Brustdrüsenschwellung der Neugeborenen. Monatsschr Kinderheilkd. 1965 Aug;113(8):497–498. [PubMed] [Google Scholar]
  11. Salazar H., Tobon H., Josimovich J. B. Developmental, gestational and postgestational modifications of the human breast. Clin Obstet Gynecol. 1975 Jun;18(2):113–137. doi: 10.1097/00003081-197506000-00007. [DOI] [PubMed] [Google Scholar]
  12. Thomson A. M., Billewicz W. Z., Hytten F. E. The assessment of fetal growth. J Obstet Gynaecol Br Commonw. 1968 Sep;75(9):903–916. doi: 10.1111/j.1471-0528.1968.tb01615.x. [DOI] [PubMed] [Google Scholar]
  13. Tobon H., Salazar H. Ultrastructure of the human mammary gland. I. Development of the fetal gland throughout gestation. J Clin Endocrinol Metab. 1974 Sep;39(3):443–456. doi: 10.1210/jcem-39-3-443. [DOI] [PubMed] [Google Scholar]
  14. Usher R., McLean F., Scott K. E. Judgment of fetal age. II. Clinical significance of gestational age and an objective method for its assessment. Pediatr Clin North Am. 1966 Aug;13(3):835–contd. doi: 10.1016/s0031-3955(16)31885-5. [DOI] [PubMed] [Google Scholar]
  15. Winter J. S., Faiman C., Reyes F. I., Hobson W. C. Gonadotrophins and steroid hormones in the blood and urine of prepubertal girls and other primates. Clin Endocrinol Metab. 1978 Nov;7(3):513–530. doi: 10.1016/s0300-595x(78)80007-3. [DOI] [PubMed] [Google Scholar]

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