Abstract
During the last 4 years we have seen 13 children with a severe bronchiolitis. The children have had prolonged respiratory illnesses waxing and waning over many months, often requiring oxygen therapy for long periods. The diagnosis is based on a clinical picture similar to acute bronchiolitis, but persisting for months, frequently associated with failure to thrive, coupled with lung function evidence of hyperinflation and airways obstruction but normal static compliance. Confusion with other chronic lung conditions can be clarified by straightforward observations and investigations. We believe that chronic bronchiolitis is fairly common and often misdiagnosed. The short- and medium-term prognosis appears good although small airways disease may persist into adult life.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Becroft D. M. Bronchiolitis obliterans, bronchiectasis, and other sequelae of adenovirus type 21 infection in young children. J Clin Pathol. 1971 Feb;24(1):72–82. doi: 10.1136/jcp.24.1.72. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cogswell J. J. Forced oscillation technique for determination of resistance to breathing in children. Arch Dis Child. 1973 Apr;48(4):259–266. doi: 10.1136/adc.48.4.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cumming G. R., Macpherson R. I., Chernick V. Unilateral hyperlucent lung syndrome in children. J Pediatr. 1971 Feb;78(2):250–260. doi: 10.1016/s0022-3476(71)80008-2. [DOI] [PubMed] [Google Scholar]
- DUBOIS A. B., BRODY A. W., LEWIS D. H., BURGESS B. F., Jr Oscillation mechanics of lungs and chest in man. J Appl Physiol. 1956 May;8(6):587–594. doi: 10.1152/jappl.1956.8.6.587. [DOI] [PubMed] [Google Scholar]
- Doershuk C. F., Downs T. D., Matthews L. W., Lough M. D. A method for ventilatory measurements in subjects 1 month--5 years of age: Normal results and observations in disease. Pediatr Res. 1970 Mar;4(2):165–174. doi: 10.1203/00006450-197003000-00007. [DOI] [PubMed] [Google Scholar]
- Hewitt C. J., Hull D., Keeling J. W. Fibrosing alveolitis in infancy and childhood. Arch Dis Child. 1977 Jan;52(1):22–37. doi: 10.1136/adc.52.1.22. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lang W. R., Howden C. W., Laws J., Burton J. F. Bronchopneumonia with serious sequelae in children with evidence of adenovirus type 21 infection. Br Med J. 1969 Jan 11;1(5636):73–79. doi: 10.1136/bmj.1.5636.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MACLEOD W. M. Abnormal transradiancy of one lung. Thorax. 1954 Jun;9(2):147–153. doi: 10.1136/thx.9.2.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Radford M. Measurement of airway resistance and thoracic gas volume in infancy. Arch Dis Child. 1974 Aug;49(8):611–615. doi: 10.1136/adc.49.8.611. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Steen-Johnsen J., Orstavik I., Attramadal A. Severe illnesses due to adenovirus type 7 in children. Acta Paediatr Scand. 1969 Mar;58(2):157–163. doi: 10.1111/j.1651-2227.1969.tb04700.x. [DOI] [PubMed] [Google Scholar]
- Stocks J., Levy N. M., Godfrey S. A new apparatus for the accurate measurement of airway resistance in infancy. J Appl Physiol Respir Environ Exerc Physiol. 1977 Jul;43(1):155–159. doi: 10.1152/jappl.1977.43.1.155. [DOI] [PubMed] [Google Scholar]
- Stokes G. M., Milner A. D., Johnson F., Hodges I. G., Groggins R. C. Measurement of work of breathing in infancy. Pediatr Res. 1981 Jan;15(1):22–27. doi: 10.1203/00006450-198101000-00006. [DOI] [PubMed] [Google Scholar]
- Wohl M. E., Chernick V. State of the art: bronchiolitis. Am Rev Respir Dis. 1978 Oct;118(4):759–781. doi: 10.1164/arrd.1978.118.4.759. [DOI] [PubMed] [Google Scholar]