Abstract
One hundred and three consecutive infants less than or equal to 32 weeks' gestation with recurrent apnoea of immaturity were reviewed, and survival was assessed and related to timing of treatment. The sickest infants were treated after between one and three episodes of apnoea with bradycardia, and mortality was 70%. Of those in whom treatment was postponed because apnoea was considered mild, 34% subsequently required mechanical ventilation, and 23% died. Among a small group of 20 survivors seen at ages 9-24 months, 4 (20%) have major handicaps. The possible place for earlier treatment is discussed.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bjerre I., Hansen E. Psychomotor development and school-adjustment of 7-year-old children with low birthweight. Acta Paediatr Scand. 1976 Jan;65(1):88–96. doi: 10.1111/j.1651-2227.1976.tb04412.x. [DOI] [PubMed] [Google Scholar]
- Eisenberg W., Holzgraefe E., Naim M. Frühgeborenen-Apnoe. Prophylaxe mit Theophyllin. Monatsschr Kinderheilkd. 1978 Aug;126(8):518–523. [PubMed] [Google Scholar]
- Jenkins S., Bax M., Hart H. Behaviour problems in pre-school children. J Child Psychol Psychiatry. 1980 Jan;21(1):5–17. doi: 10.1111/j.1469-7610.1980.tb00011.x. [DOI] [PubMed] [Google Scholar]
- Jones R. A. Apnoea of immaturity. 1. A controlled trial of theophylline and face mask continuous positive airways pressure. Arch Dis Child. 1982 Oct;57(10):761–765. doi: 10.1136/adc.57.10.761. [DOI] [PMC free article] [PubMed] [Google Scholar]