Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1983 Jun;58(6):445–450. doi: 10.1136/adc.58.6.445

Drug treatment of juvenile dermatomyositis.

G Miller, J Z Heckmatt, V Dubowitz
PMCID: PMC1627987  PMID: 6859938

Abstract

A series of 29 children with dermatomyositis has been reviewed and the outcome compared between cases treated by us initially with a low dosage short duration course of corticosteroids, and those referred late and having had various different therapeutic regimens and usually more active and higher dosage drug schedules. There were fewer relapses and less morbidity in the low dosage short term group. It was noted also that there was no relation between the initial mode of onset or severity and the eventual outcome or course of the disease. However, pronounced skin vasculitis appeared to reflect severity of disease.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BITNUM S., DAESCHNER C. W., Jr, TRAVIS L. B., DODGE W. F., HOPPS H. C. DERMATOMYOSITIS. J Pediatr. 1964 Jan;64:101–131. doi: 10.1016/s0022-3476(64)80325-5. [DOI] [PubMed] [Google Scholar]
  2. Chalmers A., Sayson R., Walters K. Juvenile dermatomyositis: medical, social and economic status in adulthood. Can Med Assoc J. 1982 Jan 1;126(1):31–33. [PMC free article] [PubMed] [Google Scholar]
  3. Coleman W. P., 3rd, coleman W. P., Derbes V. J., Jolly H. W., Jr, Nesbitt L. T., Jr Collagen disease in children. A review of 71 cases. JAMA. 1977 Mar 14;237(11):1095–1100. [PubMed] [Google Scholar]
  4. Day R. O., Pearson C. M. Primary inflammatory muscle diseases. Compr Ther. 1981 Nov;7(11):22–30. [PubMed] [Google Scholar]
  5. Dubowitz V. Treatment of dermatomyositis in childhood. Arch Dis Child. 1976 Jul;51(7):494–500. doi: 10.1136/adc.51.7.494. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lell M. E., Swerdlow M. L. Dermatomyositis of childhood. Pediatr Ann. 1977 Mar;6(3):203–212. [PubMed] [Google Scholar]
  7. Malleson P. Juvenile dermatomyositis: a review. J R Soc Med. 1982 Jan;75(1):33–37. doi: 10.1177/014107688207500110. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Medsger T. A., Jr, Robinson H., Masi A. T. Factors affecting survivorship in polymyositis. A life-table study of 124 patients. Arthritis Rheum. 1971 Mar-Apr;14(2):249–258. doi: 10.1002/art.1780140210. [DOI] [PubMed] [Google Scholar]
  9. Metzger A. L., Bohan A., Goldberg L. S., Bluestone R., Pearson C. M. Polymyositis and dermatomyositis: combined methotrexate and corticosteroid therapy. Ann Intern Med. 1974 Aug;81(2):182–189. doi: 10.7326/0003-4819-81-2-182. [DOI] [PubMed] [Google Scholar]
  10. Pachman L. M., Cooke N. Juvenile dermatomyositis: a clinical and immunologic study. J Pediatr. 1980 Feb;96(2):226–234. doi: 10.1016/s0022-3476(80)80807-9. [DOI] [PubMed] [Google Scholar]
  11. Resnick J. S., Mammel M., Mundale M. O., Kottke F. J. Muscular strength as an index of response to therapy in childhood dermatomyositis. Arch Phys Med Rehabil. 1981 Jan;62(1):12–19. [PubMed] [Google Scholar]
  12. Rose A. L. Childhood polymyositis. A follow-up study with special reference to treatment with corticosteroids. Am J Dis Child. 1974 Apr;127(4):518–522. doi: 10.1001/archpedi.1974.02110230064009. [DOI] [PubMed] [Google Scholar]
  13. Rowland L. P., Clark C., Olarte M. Therapy for dermatomyositis and polymyositis. Adv Neurol. 1977;17:63–97. [PubMed] [Google Scholar]
  14. Sullivan D. B., Cassidy J. T., Petty R. E., Burt A. Prognosis in childhood dermatomyositis. J Pediatr. 1972 Apr;80(4):555–563. doi: 10.1016/s0022-3476(72)80050-7. [DOI] [PubMed] [Google Scholar]
  15. WEDGWOOD R. J., COOK C. D., COHEN J. Dermatomyositis; report of 26 cases in children with a discussion of endocrine therapy in 13. Pediatrics. 1953 Oct;12(4):447–466. [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES