Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1983 Sep;58(9):713–716. doi: 10.1136/adc.58.9.713

Respiratory problems 2 years after acute bronchiolitis in infancy.

R L Henry, I G Hodges, A D Milner, G M Stokes
PMCID: PMC1628215  PMID: 6625633

Abstract

We assessed the clinical progress of 55 children 2 years after admission to hospital with acute bronchiolitis and performed lung function tests on 40. During the 2 year follow up period 75% of the children had wheezed, 36% had 2 or more lower respiratory symptoms lasting more than 2 weeks, 33% had more than 100 days of lower respiratory symptoms, and 13% were readmitted to hospital with acute respiratory disease. In addition 60% of the children were hyperinflated on lung function tests. Many of the children with hyperinflation at the 2 year assessment had not been hyperinflated 1 year earlier, suggesting variable airways obstruction. Reversibility of airways obstruction was also assessed by response to nebulised salbutamol. Nine children had a fall greater than 15% in airways resistance after salbutamol and these children had the highest baseline airways resistances. Airways resistance was higher in the children with a family history of atopy.

Full text

PDF
713

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burrows B., Knudson R. J., Lebowitz M. D. The relationship of childhood respiratory illness to adult obstructive airway disease. Am Rev Respir Dis. 1977 May;115(5):751–760. doi: 10.1164/arrd.1977.115.5.751. [DOI] [PubMed] [Google Scholar]
  2. Colley J. R., Douglas J. W., Reid D. D. Respiratory disease in young adults: influence of early childhood lower respiratory tract illness, social class, air pollution, and smoking. Br Med J. 1973 Jul 28;3(5873):195–198. doi: 10.1136/bmj.3.5873.195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DUBOIS A. B., BOTELHO S. Y., BEDELL G. N., MARSHALL R., COMROE J. H., Jr A rapid plethysmographic method for measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects. J Clin Invest. 1956 Mar;35(3):322–326. doi: 10.1172/JCI103281. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dementia--the quiet epidemic. Br Med J. 1978 Jan 7;1(6104):1–2. [PMC free article] [PubMed] [Google Scholar]
  5. Empey D. W., Laitinen L. A., Jacobs L., Gold W. M., Nadel J. A. Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am Rev Respir Dis. 1976 Feb;113(2):131–139. doi: 10.1164/arrd.1976.113.2.131. [DOI] [PubMed] [Google Scholar]
  6. Hatch D. J., Taylor B. W. Thoracic gas volume in early childhood. Arch Dis Child. 1976 Nov;51(11):859–864. doi: 10.1136/adc.51.11.859. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Henry R. L., Milner A. D., Stokes G. M., Hodges I. G., Groggins R. C. Lung function after acute bronchiolitis. Arch Dis Child. 1983 Jan;58(1):60–63. doi: 10.1136/adc.58.1.60. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hodges I. G., Groggins R. C., Milner A. D., Stokes G. M. Bronchodilator effect of inhaled ipratropium bromide in wheezy toddlers. Arch Dis Child. 1981 Sep;56(9):729–732. doi: 10.1136/adc.56.9.729. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kattan M., Keens T. G., Lapierre J. G., Levison H., Bryan A. C., Reilly B. J. Pulmonary function abnormalities in symptom-free children after bronchiolitis. Pediatrics. 1977 May;59(5):683–688. [PubMed] [Google Scholar]
  10. Kattan M. Long-term sequelae of respiratory illness in infancy and childhood. Pediatr Clin North Am. 1979 Aug;26(3):525–535. doi: 10.1016/s0031-3955(16)33747-6. [DOI] [PubMed] [Google Scholar]
  11. Laing I., Reidel F., Yap P. L., Simpson H. Atopy predisposing to acute bronchiolitis during an epidemic of respiratory syncytial virus. Br Med J (Clin Res Ed) 1982 Apr 10;284(6322):1070–1072. doi: 10.1136/bmj.284.6322.1070. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Lenney W., Milner A. D. At what age do bronchodilator drugs work? Arch Dis Child. 1978 Jul;53(7):532–535. doi: 10.1136/adc.53.7.532. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Mok J. Y., Simpson H. Outcome of acute lower respiratory tract infection in infants: preliminary report of seven-year follow-up study. Br Med J (Clin Res Ed) 1982 Jul 31;285(6338):333–337. doi: 10.1136/bmj.285.6338.333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Pullan C. R., Hey E. N. Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy. Br Med J (Clin Res Ed) 1982 Jun 5;284(6330):1665–1669. doi: 10.1136/bmj.284.6330.1665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rooney J. C., Williams H. E. The relationship between proved viral bronchiolitis and subsequent wheezing. J Pediatr. 1971 Nov;79(5):744–747. doi: 10.1016/s0022-3476(71)80385-2. [DOI] [PubMed] [Google Scholar]
  16. Stokes G. M., Milner A. D., Hodges I. G., Groggins R. C. Lung function abnormalities after acute bronchiolitis. J Pediatr. 1981 Jun;98(6):871–874. doi: 10.1016/s0022-3476(81)80577-x. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES