Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1983 Oct;58(10):826–828. doi: 10.1136/adc.58.10.826

Endotoxaemia in cystic fibrosis: response to antibiotics.

G Taylor, C Stern, M Silverman, M Mearns
PMCID: PMC1628287  PMID: 6416186

Abstract

In a study of 6 children with cystic fibrosis receiving intravenous antibiotics for pseudomonas lung infection, serum endotoxin values were monitored by a modification of the limulus lysate technique. The values fell with treatment, reflecting a response that was not always apparent on clinical assessment. Endotoxin concentrations may offer a more precise way of monitoring the effects of antibiotic treatment in CF patients.

Full text

PDF
826

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beaudry P. H., Marks M. I., McDougall D., Desmond K., Rangel R. Is anti-Pseudomonas therapy warranted in acute respiratory exacerbations in children with cystic fibrosis? J Pediatr. 1980 Jul;97(1):144–147. doi: 10.1016/s0022-3476(80)80155-7. [DOI] [PubMed] [Google Scholar]
  2. Prytz H., Holst-Christensen J., Korner B., Liehr H. Portal venous and systemic endotoxaemia in patients without liver disease and systemic endotoxaemia in patients with cirrhosis. Scand J Gastroenterol. 1976;11(8):857–863. [PubMed] [Google Scholar]
  3. Webster C. J. Principles of a quantitative assay for bacterial endotoxins in blood that uses Limulus lysate and a chromogenic substrate. J Clin Microbiol. 1980 Nov;12(5):644–650. doi: 10.1128/jcm.12.5.644-650.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Westphal O. Bacterial endotoxins. The second Carl Prausnitz Memorial Lecture. Int Arch Allergy Appl Immunol. 1975;49(1-2):1–43. [PubMed] [Google Scholar]
  5. Yao S. T., Gourmos C., Hobbs J. T. Detection of proximal-vein thrombosis by Doppler ultrasound flow-detection method. Lancet. 1972 Jan 1;1(7740):1–4. doi: 10.1016/s0140-6736(72)90001-3. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES