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. 1995 Sep;39(9):2164–2166. doi: 10.1128/aac.39.9.2164

Sequence and analysis of the rpoB gene of Mycobacterium smegmatis.

S V Hetherington 1, A S Watson 1, C C Patrick 1
PMCID: PMC162905  PMID: 8540740

Abstract

The rpoB gene encodes the beta subunit of the DNA-dependent RNA polymerase of bacteria. Mutations in defined areas result in resistance to rifampin. Mycobacterium smegmatis is naturally resistant to rifampin, but analysis of the rpoB gene revealed no identifiable rifampin resistance mutations. Another mechanism of resistance may be present.

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Selected References

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