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. 1995 Dec;39(12):2807–2809. doi: 10.1128/aac.39.12.2807

Thalidomide inhibits lipoarabinomannan-induced upregulation of human immunodeficiency virus expression.

P K Peterson 1, G Gekker 1, M Bornemann 1, D Chatterjee 1, C C Chao 1
PMCID: PMC163036  PMID: 8593026

Abstract

Mycobacterium tuberculosis accelerates the progression of human immunodeficiency virus type 1 (HIV-1) infection. The results of this study, which show that thalidomide inhibits the upregulation of HIV-1 expression in U1 cells stimulated with mycobacterial lipoarabinomannans, support the rationale behind conducting controlled trials of this immunodeficiency agent with patients dually infected with HIV-1 and M. tuberculosis.

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Selected References

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