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. 1977 Aug 27;2(6086):550–552. doi: 10.1136/bmj.2.6086.550

Increased exercise tolerance with nitrates in beta-blockaded patients with angina.

R H Baxter, I M Lennox
PMCID: PMC1631445  PMID: 19122

Abstract

In 14 beta-blockaded anginal subjects, 10 of whom had poor left ventricular function, sublingual isosorbide dinitrate significantly increased maximal exercise capacity on a standardized multistage treadmill test. This was associated with changes in heart rate and blood pressure suggestive of a fall in left ventricular work. The effect of isosorbide lasts for at least two hours and when taken before exercise may be a useful addition to beta-blockade in patients with angina.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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