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. 1996 Mar;40(3):809–811. doi: 10.1128/aac.40.3.809

Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis.

D Vermot 1, J M Entenza 1, J Vouillamoz 1, M P Glauser 1, P Moreillon 1
PMCID: PMC163207  PMID: 8851620

Abstract

Clarithromycin is compared with clindamycin for single-dose prophylaxis of streptococcal endocarditis in rats. Human-like kinetics of the two antibiotics prevented endocarditis in animals challenged with both small and large amounts of bacterial inocula. Clarithromycin was marginally superior to clindamycin against small amounts of inocula. Clarithromycin may be considered for endocarditis chemoprophylaxis in human.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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