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. 1977 Sep 17;2(6089):723–726. doi: 10.1136/bmj.2.6089.723

Enhanced allergic tissue injury in Goodpasture's syndrome by intercurrent bacterial infection.

A J Rees, C M Lockwood, D K Peters
PMCID: PMC1632103  PMID: 912270

Abstract

Studies of 16 relapses in seven patients receiving treatment for Goodpasture's syndrome showed that intercurrent bacterial infection seemed to be the precipitating event in 13 cases, whereas a rising antibody titre to glomerular basement membrane was responsible in only one. This association between infection and relapse in Goodpasture's syndrome has several implications for the pathogenesis of antibody-mediated tissue damage, and, clearly, more experiments are needed. Whatever the explanation, however, prevention and early diagnosis and treatment of infection in anti-GBM disease are important.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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