Abstract
Crude extracts from 115 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates were analyzed biochemically. The TEM-3 type was encountered 108 times, SHV types were encountered 7 times, and the TEM-26 type was encountered only once. For the last one, the gene was identified; an adenine was detected at position 925, as in blaTEM-26B not in blaTEM-26.
Full Text
The Full Text of this article is available as a PDF (179.0 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arlet G., Brami G., Décrè D., Flippo A., Gaillot O., Lagrange P. H., Philippon A. Molecular characterisation by PCR-restriction fragment length polymorphism of TEM beta-lactamases. FEMS Microbiol Lett. 1995 Dec 15;134(2-3):203–208. doi: 10.1111/j.1574-6968.1995.tb07938.x. [DOI] [PubMed] [Google Scholar]
- Arlet G., Philippon A. Construction by polymerase chain reaction and use of intragenic DNA probes for three main types of transferable beta-lactamases (TEM, SHV, CARB) [corrected]. FEMS Microbiol Lett. 1991 Jul 15;66(1):19–25. doi: 10.1016/0378-1097(91)90414-6. [DOI] [PubMed] [Google Scholar]
- Barthélémy M., Peduzzi J., Verchère-Beaur C., Ben Yaghlane H., Labia R. Purification and biochemical properties of Pitton's type 2 beta-lactamase (SHV-1). Ann Inst Pasteur Microbiol. 1986 Jul-Aug;137B(1):19–27. doi: 10.1016/s0769-2609(86)80090-4. [DOI] [PubMed] [Google Scholar]
- Chabbert Y. A., Scavizzi M. R., Witchitz J. L., Gerbaud G. R., Bouanchaud D. H. Incompatibility groups and the classification of fi - resistance factors. J Bacteriol. 1972 Nov;112(2):666–675. doi: 10.1128/jb.112.2.666-675.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hibbert-Rogers L. C., Heritage J., Gascoyne-Binzi D. M., Hawkey P. M., Todd N., Lewis I. J., Bailey C. Molecular epidemiology of ceftazidime resistant Enterobacteriaceae from patients on a paediatric oncology ward. J Antimicrob Chemother. 1995 Jul;36(1):65–82. doi: 10.1093/jac/36.1.65. [DOI] [PubMed] [Google Scholar]
- Hibbert-Rogers L. C., Heritage J., Todd N., Hawkey P. M. Convergent evolution of TEM-26, a beta-lactamase with extended-spectrum activity. J Antimicrob Chemother. 1994 Apr;33(4):707–720. doi: 10.1093/jac/33.4.707. [DOI] [PubMed] [Google Scholar]
- Jarlier V., Nicolas M. H., Fournier G., Philippon A. Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis. 1988 Jul-Aug;10(4):867–878. doi: 10.1093/clinids/10.4.867. [DOI] [PubMed] [Google Scholar]
- Labia R., Barthélémy M. Problèmes de la détermination des points isoélectriques des beta lactamases. C R Acad Sci Hebd Seances Acad Sci D. 1977 May 2;284(17):1729–1732. [PubMed] [Google Scholar]
- Labia R., Morand A., Tiwari K., Pitton J. S., Sirot D., Sirot J. Kinetic properties of two plasmid-mediated beta-lactamases from Klebsiella pneumoniae with strong activity against third-generation cephalosporins. J Antimicrob Chemother. 1988 Mar;21(3):301–307. doi: 10.1093/jac/21.3.301. [DOI] [PubMed] [Google Scholar]
- Labia R., Morand A., Tiwari K., Sirot J., Sirot D., Petit A. Interactions of new plasmid-mediated beta-lactamases with third-generation cephalosporins. Rev Infect Dis. 1988 Jul-Aug;10(4):885–891. doi: 10.1093/clinids/10.4.885. [DOI] [PubMed] [Google Scholar]
- Mabilat C., Courvalin P. Development of "oligotyping" for characterization and molecular epidemiology of TEM beta-lactamases in members of the family Enterobacteriaceae. Antimicrob Agents Chemother. 1990 Nov;34(11):2210–2216. doi: 10.1128/aac.34.11.2210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Meyer K. S., Urban C., Eagan J. A., Berger B. J., Rahal J. J. Nosocomial outbreak of Klebsiella infection resistant to late-generation cephalosporins. Ann Intern Med. 1993 Sep 1;119(5):353–358. doi: 10.7326/0003-4819-119-5-199309010-00001. [DOI] [PubMed] [Google Scholar]
- Naumovski L., Quinn J. P., Miyashiro D., Patel M., Bush K., Singer S. B., Graves D., Palzkill T., Arvin A. M. Outbreak of ceftazidime resistance due to a novel extended-spectrum beta-lactamase in isolates from cancer patients. Antimicrob Agents Chemother. 1992 Sep;36(9):1991–1996. doi: 10.1128/aac.36.9.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rice L. B., Marshall S. H., Carias L. L., Sutton L., Jacoby G. A. Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes. Antimicrob Agents Chemother. 1993 Dec;37(12):2760–2761. doi: 10.1128/aac.37.12.2760. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rice L. B., Willey S. H., Papanicolaou G. A., Medeiros A. A., Eliopoulos G. M., Moellering R. C., Jr, Jacoby G. A. Outbreak of ceftazidime resistance caused by extended-spectrum beta-lactamases at a Massachusetts chronic-care facility. Antimicrob Agents Chemother. 1990 Nov;34(11):2193–2199. doi: 10.1128/aac.34.11.2193. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sirot D. L., Goldstein F. W., Soussy C. J., Courtieu A. L., Husson M. O., Lemozy J., Meyran M., Morel C., Perez R., Quentin-Noury C. Resistance to cefotaxime and seven other beta-lactams in members of the family Enterobacteriaceae: a 3-year survey in France. Antimicrob Agents Chemother. 1992 Aug;36(8):1677–1681. doi: 10.1128/aac.36.8.1677. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sirot J., Chanal C., Petit A., Sirot D., Labia R., Gerbaud G. Klebsiella pneumoniae and other Enterobacteriaceae producing novel plasmid-mediated beta-lactamases markedly active against third-generation cephalosporins: epidemiologic studies. Rev Infect Dis. 1988 Jul-Aug;10(4):850–859. doi: 10.1093/clinids/10.4.850. [DOI] [PubMed] [Google Scholar]
- Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
- Takahashi S., Nagano Y. Rapid procedure for isolation of plasmid DNA and application to epidemiological analysis. J Clin Microbiol. 1984 Oct;20(4):608–613. doi: 10.1128/jcm.20.4.608-613.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Urban C., Meyer K. S., Mariano N., Rahal J. J., Flamm R., Rasmussen B. A., Bush K. Identification of TEM-26 beta-lactamase responsible for a major outbreak of ceftazidime-resistant Klebsiella pneumoniae. Antimicrob Agents Chemother. 1994 Feb;38(2):392–395. doi: 10.1128/aac.38.2.392. [DOI] [PMC free article] [PubMed] [Google Scholar]
