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. 1974 Jan 19;1(5898):94–96. doi: 10.1136/bmj.1.5898.94

Assessment of Fetal Lung Maturity by Estimation of Amniotic Fluid Palmitic Acid

Christine Warren, J B Holton, J T Allen
PMCID: PMC1632929  PMID: 4859701

Abstract

The measurement of palmitic acid in amniotic fluid has been shown to be a rapid means of assessing the lecithin concentration. The level of palmitic acid increases quickly when the fetal lung matures at about 35 weeks' gestation, and the level in amniotic fluid obtained 24 hours or less before delivery clearly distinguishes which infants are likely to develop respiratory distress syndrome and which are mature.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bhagwanani S. G., Fahmy D., Turnbull A. C. Quick determination of amniotic-fluid lecithin concentration for prediction of neonatal respiratory distress. Lancet. 1972 Jul 8;2(7767):66–67. doi: 10.1016/s0140-6736(72)91554-1. [DOI] [PubMed] [Google Scholar]
  2. Gluck L., Kulovich M. V., Borer R. C., Jr, Brenner P. H., Anderson G. G., Spellacy W. N. Diagnosis of the respiratory distress syndrome by amniocentesis. Am J Obstet Gynecol. 1971 Feb 1;109(3):440–445. doi: 10.1016/0002-9378(71)90342-5. [DOI] [PubMed] [Google Scholar]
  3. MacDonald H. N., Isherwood D. M. Assessment of gestational age from amniotic fluid. Lancet. 1972 Feb 5;1(7745):321–322. doi: 10.1016/s0140-6736(72)90329-7. [DOI] [PubMed] [Google Scholar]
  4. Warren C., Allen J. T., Holton J. B. Assessment of foetal lung maturity by amniotic fluid fatty acid analysis. Clin Chim Acta. 1973 Mar 30;44(3):457–459. doi: 10.1016/0009-8981(73)90093-4. [DOI] [PubMed] [Google Scholar]
  5. Whitfield C. R., Sproule W. B. Neonatal respiratory distress. Lancet. 1972 Feb 12;1(7746):382–382. doi: 10.1016/s0140-6736(72)92880-2. [DOI] [PubMed] [Google Scholar]

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