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. 1996 Jul;40(7):1736–1740. doi: 10.1128/aac.40.7.1736

Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 beta-lactamase (LAT-2).

M Gazouli 1, L S Tzouvelekis 1, E Prinarakis 1, V Miriagou 1, E Tzelepi 1
PMCID: PMC163408  PMID: 8807075

Abstract

Cefoxitin resistance in Klebsiella pneumoniae from Escherichia coli strains isolated in Greek hospitals was found to be due to the acquisition of similar plasmids coding for group 1 beta-lactamases. The plasmids were not self-transferable but were mobilized by conjugative plasmids. These elements have also been spread to Enterobacter aerogenes. The most common enzyme was a Citrobacter freundii-derived cephalosporinase (LAT-2) which differed from LAT-1 by three amino acids.

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Selected References

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