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. 1997 Oct;41(10):2295–2296. doi: 10.1128/aac.41.10.2295

Low-level release of Shiga-like toxin (verocytotoxin) and endotoxin from enterohemorrhagic Escherichia coli treated with imipenem.

K Takahashi 1, K Narita 1, Y Kato 1, T Sugiyama 1, N Koide 1, T Yoshida 1, T Yokochi 1
PMCID: PMC164112  PMID: 9333067

Abstract

Shiga-like toxin (SLT) and endotoxin may participate in the pathogenesis of enterohemorrhagic Escherichia coli (EHEC) infection. Levels of release of SLT and endotoxin from EHEC treated in vitro with antibiotics were estimated. There were differential levels of release of SLT and endotoxin from EHEC treated with different antibiotics. Treatment of EHEC strains, namely, E. coli O157, O111, and O26, with imipenem induced much lower levels of release of SLT and endotoxin than treatment with ceftazidime.

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Selected References

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