Abstract
In a case-control study, we investigated the relation of cigarette smoking and genital herpes virus infection to cervical abnormalities. Although cases and controls differed according to several factors, multiple logistic analyses indicated that age, education, and cigarette smoking were the only independent risk factors for histologically confirmed disease. Relative risk estimates were 1.92 and 3.68 for past and current smokers, respectively. The results indicated that smoking and genital herpes infection did not interact in the risk of cervical abnormality.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Buckley J. D., Harris R. W., Doll R., Vessey M. P., Williams P. T. Case-control study of the husbands of women with dysplasia or carcinoma of the cervix uteri. Lancet. 1981 Nov 7;2(8254):1010–1015. doi: 10.1016/s0140-6736(81)91215-0. [DOI] [PubMed] [Google Scholar]
- Clarke E. A., Morgan R. W., Newman A. M. Smoking as a risk factor in cancer of the cervix: additional evidence from a case-control study. Am J Epidemiol. 1982 Jan;115(1):59–66. doi: 10.1093/oxfordjournals.aje.a113279. [DOI] [PubMed] [Google Scholar]
- Harris R. W., Brinton L. A., Cowdell R. H., Skegg D. C., Smith P. G., Vessey M. P., Doll R. Characteristics of women with dysplasia or carcinoma in situ of the cervix uteri. Br J Cancer. 1980 Sep;42(3):359–369. doi: 10.1038/bjc.1980.246. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lyon J. L., Gardner J. W., West D. W., Stanish W. M., Hebertson R. M. Smoking and carcinoma in situ of the uterine cervix. Am J Public Health. 1983 May;73(5):558–562. doi: 10.2105/ajph.73.5.558. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MANTEL N., HAENSZEL W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 Apr;22(4):719–748. [PubMed] [Google Scholar]
- Marshall J. R., Graham S., Byers T., Swanson M., Brasure J. Diet and smoking in the epidemiology of cancer of the cervix. J Natl Cancer Inst. 1983 May;70(5):847–851. [PubMed] [Google Scholar]
- Menczer J., Leventon-Kriss S., Modan M., Oelsner G., Gerichter C. B. Antibodies to Herpes simplex virus in Jewish women with cervical cancer and in healthy Jewish women of Israel. J Natl Cancer Inst. 1975 Jul;55(1):3–6. doi: 10.1093/jnci/55.1.3. [DOI] [PubMed] [Google Scholar]
- Miettinen O. Confounding and effect-modification. Am J Epidemiol. 1974 Nov;100(5):350–353. doi: 10.1093/oxfordjournals.aje.a112044. [DOI] [PubMed] [Google Scholar]
- Nahmias A. J., Sawanabori S. The genital herpes-cervical cancer hypothesis--10 years later. Prog Exp Tumor Res. 1978;21:117–139. doi: 10.1159/000400861. [DOI] [PubMed] [Google Scholar]
- Pridan H., Lilienfeld A. M. Carcinoma of the cervix in Jewish women in Israel, 1960-67. An epidemiological study. Isr J Med Sci. 1971 Dec;7(12):1465–1470. [PubMed] [Google Scholar]
- ROTKIN I. D. Relation of adolescent coitus to cervical cancer risk. JAMA. 1962 Feb 17;179:486–491. doi: 10.1001/jama.1962.03050070008002. [DOI] [PubMed] [Google Scholar]
- Rotkin I. D. A comparison review of key epidemiological studies in cervical cancer related to current searches for transmissible agents. Cancer Res. 1973 Jun;33(6):1353–1367. [PubMed] [Google Scholar]
- Schachter J., Hill E. C., King E. B., Heilbron D. C., Ray R. M., Margolis A. J., Greenwood S. A. Chlamydia trachomatis and cervical neoplasia. JAMA. 1982 Nov 5;248(17):2134–2138. [PubMed] [Google Scholar]
- Trevathan E., Layde P., Webster L. A., Adams J. B., Benigno B. B., Ory H. Cigarette smoking and dysplasia and carcinoma in situ of the uterine cervix. JAMA. 1983 Jul 22;250(4):499–502. [PubMed] [Google Scholar]
- Wigle D. T., Mao Y., Grace M. Re: "Smoking and cancer of the uterine cervix: hypothesis". Am J Epidemiol. 1980 Jan;111(1):125–127. doi: 10.1093/oxfordjournals.aje.a112862. [DOI] [PubMed] [Google Scholar]
- Winkelstein W., Jr Smoking and cancer of the uterine cervix: hypothesis. Am J Epidemiol. 1977 Oct;106(4):257–259. doi: 10.1093/oxfordjournals.aje.a112460. [DOI] [PubMed] [Google Scholar]