Abstract
As a result of New York State's Newborn Screening Program 4,565 neonates with trait hemoglobinopathies were identified and 3,200 families were notified of the results of testing their infants in New York City in 1982. Of the 1,531 families (2,190 parents) tested and counseled, 22 parents were diagnosed with sickle cell disease and 39 couples were found to be at-risk for having a child with sickle cell disease. Amniocentesis was performed in 14 of the 28 at-risk pregnant women and three of the four affected pregnancies were terminated. MCH-331001-01 to 04
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Garrick M. D., Dembure P., Guthrie R. Sickle-cell anemia and other hemoglobinopathies. Procedures and strategy for screening employing spots of blood on filter paper as specimens. N Engl J Med. 1973 Jun 14;288(24):1265–1268. doi: 10.1056/NEJM197306142882403. [DOI] [PubMed] [Google Scholar]
- Geever R. F., Wilson L. B., Nallaseth F. S., Milner P. F., Bittner M., Wilson J. T. Direct identification of sickle cell anemia by blot hybridization. Proc Natl Acad Sci U S A. 1981 Aug;78(8):5081–5085. doi: 10.1073/pnas.78.8.5081. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Grover R., Shahidi S., Fisher B., Goldberg D., Wethers D. Current sickle cell screening program for newborns in New York City, 1979-1980. Am J Public Health. 1983 Mar;73(3):249–252. doi: 10.2105/ajph.73.3.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Headings V. E. Sickle cell disease in childhood. Strategies for early diagnosis. Am J Pediatr Hematol Oncol. 1982 Spring;4(1):67–71. [PubMed] [Google Scholar]
- Leonard C. O., Kazazian H. H., Jr Prenatal diagnosis of hemoglobinopathies. Pediatr Clin North Am. 1978 Aug;25(3):631–642. doi: 10.1016/s0031-3955(16)33608-2. [DOI] [PubMed] [Google Scholar]
- Pearson H. A., O'Brien R. T., McIntosh S., Aspnes G. T., Yang M. M. Routine screening of umbilical cord blood for sickle cell diseases. JAMA. 1974 Jan 28;227(4):420–421. [PubMed] [Google Scholar]
- Scott R. B., Harrison D. L. Screening of the umbilical cord blood for sickle cell disease: utilization and implementation. Am J Pediatr Hematol Oncol. 1982 Summer;4(2):202–205. [PubMed] [Google Scholar]
- Scriver C. H. Genetic screening: implications for preventive medicine. Am J Public Health. 1983 Mar;73(3):243–245. doi: 10.2105/ajph.73.3.243. [DOI] [PMC free article] [PubMed] [Google Scholar]