Abstract
Simultaneous outbreaks of S. sonnei infections occurred in September 1983 at two day care centers in Seattle, Washington. At both centers, there were high rates of diarrheal illness in the children (22/80 and 11/23, respectively), in staff members, and in family members of the ill children. The smaller center was temporarily closed, but the larger one remained open. Convalescent children and staff whose diarrhea had resolved and who were receiving appropriate antimicrobials were allowed to return to the larger center before negative cultures were obtained and were separated in an isolation room. No culture-proven cases of shigellosis occurred at either center in the following two months. Plasmid profile determinations suggested the Shigella were not transmitted from the center that remained open to the community. Estimated need for alternate child care requirements at the closed center were 100-fold greater than at the center with the isolation room. Caring for convalescent children in isolation at day care centers while they receive antimicrobial therapy may be a useful strategy for controlling day care shigellosis.
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Selected References
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- Baine W. B., Herron C. A., Bridson K., Barker W. H., Jr, Lindell S., Mallison G. F., Wells J. G., Martin W. T., Kosuri M. R., Carr F. Waterborne shigellosis at a public school. Am J Epidemiol. 1975 Apr;101(4):323–332. doi: 10.1093/oxfordjournals.aje.a112100. [DOI] [PubMed] [Google Scholar]
- Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
- Birnboim H. C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 1979 Nov 24;7(6):1513–1523. doi: 10.1093/nar/7.6.1513. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Black R. E., Dykes A. C., Anderson K. E., Wells J. G., Sinclair S. P., Gary G. W., Jr, Hatch M. H., Gangarosa E. J. Handwashing to prevent diarrhea in day-care centers. Am J Epidemiol. 1981 Apr;113(4):445–451. doi: 10.1093/oxfordjournals.aje.a113112. [DOI] [PubMed] [Google Scholar]
- HUTCHINSON R. I. Some observations on the method of spread of Sonne dysentery. Mon Bull Minist Health Public Health Lab Serv. 1956 Jun;15:110–118. [PubMed] [Google Scholar]
- Haltalin K. C., Kusmiesz H. T., Hinton L. V., Nelson J. D. Treatment of acute diarrhea in outpatients. Double-blind study comparing ampicillin and placebo. Am J Dis Child. 1972 Oct;124(4):554–561. doi: 10.1001/archpedi.1972.02110160092010. [DOI] [PubMed] [Google Scholar]
- Morris G. K., Wells J. G. Colicin typing of Shigella sonnei. Appl Microbiol. 1974 Feb;27(2):312–316. doi: 10.1128/am.27.2.312-316.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nelson J. D., Haltalin K. C. Broad-spectrum penicillins in enteric infections of children. Ann N Y Acad Sci. 1967 Sep 27;145(2):414–422. doi: 10.1111/j.1749-6632.1967.tb50240.x. [DOI] [PubMed] [Google Scholar]
- Pickering L. K., Evans D. G., DuPont H. L., Vollet J. J., 3rd, Evans D. J., Jr Diarrhea caused by Shigella, rotavirus, and Giardia in day-care centers: prospective study. J Pediatr. 1981 Jul;99(1):51–56. doi: 10.1016/s0022-3476(81)80956-0. [DOI] [PubMed] [Google Scholar]
- Tacket C. O., Cohen M. L. Shigellosis in day care centers: use of plasmid analysis to assess control measures. Pediatr Infect Dis. 1983 Mar-Apr;2(2):127–130. [PubMed] [Google Scholar]
- Weissman J. B., Gangarosa E. J., Dupont H. L., Nelson J. D., Haltalin K. C. Shigellosis. To treat or not to treat? JAMA. 1974 Aug 26;229(9):1215–1216. doi: 10.1001/jama.229.9.1215. [DOI] [PubMed] [Google Scholar]
- Weissman J. B., Schmerler A., Weiler P., Filice G., Godbey N., Hansen I. The role of preschool children and day-care centers in the spread of shigellosis in urban communities. J Pediatr. 1974 Jun;84(6):797–802. doi: 10.1016/s0022-3476(74)80750-x. [DOI] [PubMed] [Google Scholar]
- Weissman J. B., Williams S. V., Hinman A. R., Haughie G. R., Gangarosa E. J. Foodborne shigellosis at a country fair. Am J Epidemiol. 1974 Sep;100(3):178–185. doi: 10.1093/oxfordjournals.aje.a112026. [DOI] [PubMed] [Google Scholar]
- Wilson R., Feldman R. A., Davis J., LaVenture M. Family illness associated with Shigella infection: the interrelationship of age of the index patient and the age of household members in acquisition of illness. J Infect Dis. 1981 Jan;143(1):130–132. doi: 10.1093/infdis/143.1.130. [DOI] [PubMed] [Google Scholar]