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Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1971 Apr;46(246):152–159. doi: 10.1136/adc.46.246.152

Effect of Alterations in Mechanical Ventilator Settings on Pulmonary Gas Exchange in Hyaline Membrane Disease

E O R Reynolds
PMCID: PMC1647476  PMID: 5576023

Abstract

The effect of altering peak airway pressure, respiratory frequency, and inspiration: expiration ratio on arterial blood gas tensions, blood pressure, and calculated right-to-left shunt was investigated in 6 infants undergoing mechanical ventilation for hyaline membrane disease with a Bennet ventilator. The use of a very long inspiratory phase resulted in a large increase in Pao2 and fall in right-to-left shunt without affecting mean arterial blood pressure.

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Selected References

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