Abstract
Two infants are described who developed renal tubular and papillary necrosis. In one, severe problems of management occurred during the diuretic phase. In the other, the intravenous pyelogram showed characteristic changes during the acute illness. The urinary findings are compared with those in other dehydrated infants and a means of early diagnosis is suggested. In a dehydrated infant an initial urine sodium of more than 100 mEq/l., the persistence of osmolality below 500 mOsm/kg, and urea below 1500 mg/100 ml suggest renal tubular damage.
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- Barr D. G., Forfar J. O. Oral calcium-loading test in infancy, with particular reference to idiopathic hypercalcaemia. Br Med J. 1969 Feb 22;1(5642):477–480. doi: 10.1136/bmj.1.5642.477. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chrispin A. R., Hull D., Lillie J. G., Ridson R. A. Renal tubular necrosis and papillary necrosis after gastroenteritis in infants. Br Med J. 1970 Feb 14;1(5693):410–412. doi: 10.1136/bmj.1.5693.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mauer S. M., Nogrady M. B. Renal papillary and cortical necrosis in a newborn infant: report of a survivor with roentgenologic documentation. J Pediatr. 1969 May;74(5):750–754. doi: 10.1016/s0022-3476(69)80137-x. [DOI] [PubMed] [Google Scholar]
- RUSH B. F., Jr, FINBERG L., DAVIGLUS G. F., CHEUNG C. S. Pathologic lesions in experimental hypernatremia induced by extracorporeal dialysis. Surgery. 1961 Aug;50:359–366. [PubMed] [Google Scholar]
- Risdon R. A., Berry C. L., Chrispin A. R. Urographic changes in acute papillary necrosis in the rat. Br Med J. 1970 Aug 1;3(5717):263–265. doi: 10.1136/bmj.3.5717.263. [DOI] [PMC free article] [PubMed] [Google Scholar]