Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1972 Dec;47(256):941–945. doi: 10.1136/adc.47.256.941

Total Body Water Content of Neonates with Obstruction of Alimentary Tract

Stavros Tsingoglou, Harriett Phillips, Andrew W Wilkinson
PMCID: PMC1648402  PMID: 4567075

Abstract

The total body water content was measured by the deuterium oxide dilution method in 55 neonates admitted to hospital for surgical treatment within 90 hours of birth. The mean total body water of the whole group was 77·03 ± 0·62 (SEM)% of the body weight (range 67·4 to 88·6%), or 1·974 ± 0·005 (SEM) litres (range 1·010 to 2·830 litres). Over a range of body weights from 1·160 to 3·851 kg, total body water content expressed as a percentage of body weight decreased by 5% per kg rise in body weight, but when expressed as litres per kg body weight it increased by 737 ml for each rise of 1 kg in body weight. There was a small difference in water content between babies with obstruction of the alimentary tract and those with other nonobstructive lesions, which was not statistically significant.

Full text

PDF
941

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cassady G. Bromide space studies in infants of low birth weight. Pediatr Res. 1970 Jan;4(1):14–24. doi: 10.1203/00006450-197001000-00002. [DOI] [PubMed] [Google Scholar]
  2. FALLER I. L., PETTY D., LAST J. H., PASCALE L. R., BOND E. E. A comparison of the deuterium oxide and antipyrine dilution methods for measuring total body water in normal and hydropic human subjects. J Lab Clin Med. 1955 May;45(5):748–758. [PubMed] [Google Scholar]
  3. Maclaurin J. C. Changes in body water distribution during the first two weeks of life. Arch Dis Child. 1966 Jun;41(217):286–291. doi: 10.1136/adc.41.217.286. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. SCHLOERB P. R., FRIIS-HANSEN B. J., EDELMAN I. S., SOLOMON A. K., MOORE F. D. The measurement of total body water in the human subject by deuterium oxide dilution; with a consideration of the dynamics of deuterium distribution. J Clin Invest. 1950 Oct;29(10):1296–1310. doi: 10.1172/JCI102366. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. TURNER M. D., NEELY W. A., HARDY J. D. Rapid determination of deuterium oxide in biological fluids. J Appl Physiol. 1960 Mar;15:309–310. doi: 10.1152/jappl.1960.15.2.309. [DOI] [PubMed] [Google Scholar]
  6. WILKINSON A. W., STEVENS L. H., HUGHES E. A. Metabolic changes in the newborn. Lancet. 1962 May 12;1(7237):983–987. doi: 10.1016/s0140-6736(62)92029-9. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES