Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1973 Sep;48(9):717–720. doi: 10.1136/adc.48.9.717

Rates of creatinine clearance in babies less than one week of age

Hüseyin Sertel, Jon Scopes
PMCID: PMC1648482  PMID: 4733641

Abstract

Rates of creatinine clearance were measured in normal newborn babies by collecting a timed specimen of voided urine and estimating plasma creatinine. Each of the 17 babies had the estimation on day 1 and on day 6 of life. The mean rate on day 1 was 17·8 ml/minute per 1·73 m2, and there was a significant and systematic increase by day 6 when the mean rate was 36·4 ml/minute per 1·73 m2. The findings are important when assessing fluid requirements and drug dosage in the newborn.

Full text

PDF
717

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dean R. F., McCance R. A. Inulin, diodone, creatinine and urea clearances in newborn infants. J Physiol. 1947 Oct 15;106(4):431–439. doi: 10.1113/jphysiol.1947.sp004224. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. JOSEPHSON B., FURST P., JARNMARK O. Age variations in the concentration of non-protein nitrogen, creatinine and urea in blood of infants and children. Acta Paediatr Suppl. 1962 Jun;135:111–120. doi: 10.1111/j.1651-2227.1962.tb08665.x. [DOI] [PubMed] [Google Scholar]
  3. WINBERG J. The 24-hour true endogenous creatinine clearance in infants and children without renal disease. Acta Paediatr. 1959 Sep;48:443–452. [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES