Abstract
Hyperoxaluria was found in 4 of 10 children who had had resection of the ileum. There was no relation between hyperoxaluria and the length of the resection or period since the resection. Previous studies have shown reduced ratios of taurine-conjugated to glycine-conjugated bile salts in the small intestine after ileal resection and we have found low levels of taurine in the urine of these patients. There was no correlation between the urinary taurine level and hyperoxaluria. In view of the variable excretion of oxalate in some patients, the high incidence of renal stones in adults with secondary hyperoxaluria, and the possibility of dietary treatment, regular estimations of urinary oxalate should be performed in children who have had resection of the ileum.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Admirand W. H., Earnest D. L., Williams H. E. Hyperoxaluria and bowel disease. Trans Assoc Am Physicians. 1971;84:307–312. [PubMed] [Google Scholar]
- Chadwick V. S., Modha K., Dowling R. H. Mechanism for hyperoxaluria in patients with ileal dysfunction. N Engl J Med. 1973 Jul 26;289(4):172–176. doi: 10.1056/NEJM197307262890402. [DOI] [PubMed] [Google Scholar]
- Dowling R. H., Rose G. A., Sutor D. J. Hyperoxaluria and renal calculi in ileal disease. Lancet. 1971 May 29;1(7709):1103–1106. doi: 10.1016/s0140-6736(71)91840-x. [DOI] [PubMed] [Google Scholar]
- Evered D. F., Harvey M. S., Luck L. J., Solari M. E. The relationship between urinary taurine excretion and the intake of protein-rich foods. Life Sci. 1969 Jun 15;8(12):601–605. doi: 10.1016/0024-3205(69)90215-x. [DOI] [PubMed] [Google Scholar]
- Gibbs D. A., Watts R. W. The variation of urinary oxalate excretion with age. J Lab Clin Med. 1969 Jun;73(6):901–908. [PubMed] [Google Scholar]
- Giterson A. L., Slooff P. A., Schouten H. Oxalate in urine. Clin Chim Acta. 1970 Aug;29(2):342–343. doi: 10.1016/0009-8981(70)90058-6. [DOI] [PubMed] [Google Scholar]
- HOCKADAY T. D., FREDERICK E. W., CLAYTON J. E., SMITH L. H., Jr STUDIES ON PRIMARY HYPEROXALURIA. II. URINARY OXALATE, GLYCOLATE, AND GLYOXYLATE MEASUREMENT BY ISOTOPE DILUTION METHODS. J Lab Clin Med. 1965 Apr;65:677–687. [PubMed] [Google Scholar]
- McLeod G. M., Wiggins H. S. Bile-salts in small intestinal contents after ileal resection and in other malabsorption syndromes. Lancet. 1968 Apr 27;1(7548):873–876. doi: 10.1016/s0140-6736(68)90235-3. [DOI] [PubMed] [Google Scholar]
- Smith L. H., Fromm H., Hofmann A. F. Acquired hyperoxaluria, nephrolithiasis, and intestinal disease. Description of a syndrome. N Engl J Med. 1972 Jun 29;286(26):1371–1375. doi: 10.1056/NEJM197206292862601. [DOI] [PubMed] [Google Scholar]
- Stauffer J. Q., Humphreys M. H. Hyperoxaluria with intestinal disease. N Engl J Med. 1972 Aug 24;287(8):412–412. doi: 10.1056/NEJM197208242870815. [DOI] [PubMed] [Google Scholar]