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. 1974 Jan;49(1):60–62. doi: 10.1136/adc.49.1.60

Phototherapy for hyperbilirubinaemia in low birthweight infants

Elizabeth Elliott, M W Moncrieff, W H S George
PMCID: PMC1648833  PMID: 4818094

Abstract

Eighty-eight babies whose birthweights were between 1500 g and 2500 g, and whose serum bilirubin reached 10 mg/100 ml, were entered into a controlled trial of phototherapy. Alternate babies were treated with 4000 to 5000 lux, and control cases were not treated unless the bilirubin exceeded 15 mg/100 ml. No baby in the treated group developed a serum bilirubin greater than 15 mg/100 ml, compared with 44% of untreated cases, a highly significant difference. No side effects occurred apart from overheating in a few babies. We conclude that phototherapy is a safe and effective way of treating hyperbilirubinaemia in low birthweight infants, and suggest it should be started when the bilirubin reaches 12 mg/100 ml, except for babies under 1500 g birthweight when it should be started at 10 mg/100 ml.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CREMER R. J., PERRYMAN P. W., RICHARDS D. H. Influence of light on the hyperbilirubinaemia of infants. Lancet. 1958 May 24;1(7030):1094–1097. doi: 10.1016/s0140-6736(58)91849-x. [DOI] [PubMed] [Google Scholar]
  2. Gartner L. M., Snyder R. N., Chabon R. S., Bernstein J. Kernicterus: high incidence in premature infants with low serum bilirubin concentrations. Pediatrics. 1970 Jun;45(6):906–917. [PubMed] [Google Scholar]
  3. Giunta F. A 1-year experience with phototherapy for jaundice of prematurity. Pediatrics. 1971 Jan;47(1):123–125. [PubMed] [Google Scholar]
  4. Hodgman J. E., Schwartz A. Phototherapy and hyperbilirubinemia of the premature. Am J Dis Child. 1970 Jun;119(6):473–477. doi: 10.1001/archpedi.1970.02100050475003. [DOI] [PubMed] [Google Scholar]
  5. Lucey J., Ferriero M., Hewitt J. Prevention of hyperbilirubinemia of prematurity by phototherapy. Pediatrics. 1968 Jun;41(6):1047–1054. [PubMed] [Google Scholar]
  6. MCKAY R. J., Jr CURRENT STATUS OF USE OF EXCHANGE TRANSFUSION IN NEWBORN INFANTS. Pediatrics. 1964 May;33:763–767. [PubMed] [Google Scholar]
  7. Porto S. O., Pildes R. S., Goodman H. Studies on the effects of phototherapy on neonatal hyperbilirubinemia among low-birth-weht infants. I. Skin color. J Pediatr. 1969 Dec;75(6):1045–1047. doi: 10.1016/s0022-3476(69)80344-6. [DOI] [PubMed] [Google Scholar]
  8. Tabb P. A., Savage D. C., Inglis J., Walker C. H. Controlled trial of phototherapy of limited duration in the treatment of physiological hyperbilirubinaemia in low-birth-weight infants. Lancet. 1972 Dec 9;2(7789):1211–1212. doi: 10.1016/s0140-6736(72)92265-9. [DOI] [PubMed] [Google Scholar]
  9. Usher R., McLean F., Scott K. E. Judgment of fetal age. II. Clinical significance of gestational age and an objective method for its assessment. Pediatr Clin North Am. 1966 Aug;13(3):835–contd. doi: 10.1016/s0031-3955(16)31885-5. [DOI] [PubMed] [Google Scholar]
  10. Washington J. L., Brown A. W., Starrett A. L. The question of diarrhea and phototherapy. Pediatrics. 1972 Feb;49(2):279–280. [PubMed] [Google Scholar]

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