Abstract
The electrolyte concentration of the vitreous humour of the eye in a consecutive series of 40 infants dying unexpectedly at home was measured. In 25 of these infants no morbid anatomical cause of death was found, but in half of these infants analysis of the vitreous humour indicated the presence of hypernatraemia, either with or without uraemia. High solute feeding and water deficiency could therefore have been a major factor in the death of these infants.
Estimation of the vitreous electrolytes is an essential part of examination of children falling within the `cot death' group.
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Selected References
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- ADELSON L., SUNSHINE I., RUSHFORTH N. B., MANKOFF M. VITREOUS POTASSIUM CONCENTRATION AS AN INDICATOR OF THE POSTMORTEM INTERVAL. J Forensic Sci. 1963 Oct;8(4):503–514. [PubMed] [Google Scholar]
- Caddell J. L. Magnesium deprivation in sudden unexpected infant death. Lancet. 1972 Aug 5;2(7771):258–262. doi: 10.1016/s0140-6736(72)91690-x. [DOI] [PubMed] [Google Scholar]
- Coe J. I., Sherman R. E. Comparative study of postmortem vitreous humor and blood alcohol. J Forensic Sci. 1970 Apr;15(2):185–190. [PubMed] [Google Scholar]
- Davies D. P. Plasma osmolality and feeding practices of healthy infants in first three months of life. Br Med J. 1973 May 12;2(5862):340–342. doi: 10.1136/bmj.2.5862.340. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ferris J. A., Aherne W. A., Locke W. S., McQuillin J., Gardner P. S. Sudden and unexpected deaths in infants: histology and virology. Br Med J. 1973 May 26;2(5864):439–442. doi: 10.1136/bmj.2.5864.439. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Froggatt P., Lynas M. A., MacKenzie G. Epidemiology of sudden unexpected death in infants ('cot death') in Northern Ireland. Br J Prev Soc Med. 1971 Aug;25(3):119–134. doi: 10.1136/jech.25.3.119. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gardner P. S. Virus infections and respiratory disease of childhood. Arch Dis Child. 1968 Dec;43(232):629–645. doi: 10.1136/adc.43.232.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARRISON H. E., FINBERG L. Hypernatremic dehydration. Pediatr Clin North Am. 1959 Feb;6(1):193–199. doi: 10.1016/s0031-3955(16)30768-4. [DOI] [PubMed] [Google Scholar]
- Heggarty H., Trindade P., Bryan E. M. Hyperglycaemia in hyperosmolar dehydration. Arch Dis Child. 1973 Sep;48(9):740–741. doi: 10.1136/adc.48.9.740. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hodgkinson A., Hambleton J. Elevation of serum calcium concentration and changes in other blood parameters after death. J Surg Res. 1969 Oct;9(10):567–574. doi: 10.1016/0022-4804(69)90012-2. [DOI] [PubMed] [Google Scholar]
- Macaulay D., Watson M. Hypernatraemia in infants as a cause of brain damage. Arch Dis Child. 1967 Oct;42(225):485–491. doi: 10.1136/adc.42.225.485. [DOI] [PMC free article] [PubMed] [Google Scholar]
- NAUMANN H. N. Postmortem chemistry of the vitreous body in man. Arch Ophthalmol. 1959 Sep;62:356–363. doi: 10.1001/archopht.1959.04220030012003. [DOI] [PubMed] [Google Scholar]
- NAUMANN H. N. Studies on postmortem chemistry. Am J Clin Pathol. 1950 Apr;20(4):314–324. doi: 10.1093/ajcp/20.4.314. [DOI] [PubMed] [Google Scholar]
- STURNER W. Q., GANTNER G. E., Jr THE POSTMORTEM INTERVAL. A STUDY OF POTASSIUM IN THE VITREOUS HUMOR. Am J Clin Pathol. 1964 Aug;42:137–144. doi: 10.1093/ajcp/42.2.137. [DOI] [PubMed] [Google Scholar]
- Stowens D., Callahan E. L., Clay J. Sudden unexpected death in infancy. A new hypothesis of cause. Clin Pediatr (Phila) 1966 Apr;5(4):243–254. doi: 10.1177/000992286600500415. [DOI] [PubMed] [Google Scholar]
- Sturner W. Q., Dempsey J. L. Sudden infant death: chemical analysis of vitreous humor. J Forensic Sci. 1973 Jan;18(1):12–19. [PubMed] [Google Scholar]
- Swift P. G., Worthy E., Emery J. L. Biochemical state of the vitreous humour of infants at necropsy. Arch Dis Child. 1974 Sep;49(9):680–685. doi: 10.1136/adc.49.9.680. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Taitz L. S., Byers H. D. High calorie-osmolar feeding and hypertonic dehydration. Arch Dis Child. 1972 Apr;47(252):257–260. doi: 10.1136/adc.47.252.257. [DOI] [PMC free article] [PubMed] [Google Scholar]
