Abstract
Records of 642 outbreaks of acute gastroenteritis were reviewed to determine the proportion of outbreaks that were clinically and epidemiologically consistent with Norwalk-like virus infection. Using as our criteria stool cultures negative for bacterial pathogens, mean (or median) duration of illness 12-60 hours, vomiting in greater than or equal to 50 per cent of cases, and, if known, mean (or median) incubation period of 24-48 hours, we found that 23 per cent of waterborne outbreaks, 4 per cent of foodborne outbreaks, and 67 per cent, 60 per cent, and 28 per cent of outbreaks in nursing homes, in summer camps, and on cruise ships, respectively, satisfied the criteria for Norwalk-like pattern. Of 54 outbreaks that satisfied the criteria for Norwalk-like pattern, 14 were investigated for virus etiology. Ten of these (71 per cent) yielded serologic evidence of Norwalk-like virus infection. Norwalk-like viruses are probably an important cause of outbreaks of acute gastroenteritis. Investigation for Norwalk virus antibody in outbreaks that are clinically and epidemiologically consistent with Norwalk-like virus infection is likely to yield diagnostically useful results.
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Selected References
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- Blacklow N. R., Cukor G. Viral gastroenteritis. N Engl J Med. 1981 Feb 12;304(7):397–406. doi: 10.1056/NEJM198102123040705. [DOI] [PubMed] [Google Scholar]
- Blaser M. J., Berkowitz I. D., LaForce F. M., Cravens J., Reller L. B., Wang W. L. Campylobacter enteritis: clinical and epidemiologic features. Ann Intern Med. 1979 Aug;91(2):179–185. doi: 10.7326/0003-4819-91-2-179. [DOI] [PubMed] [Google Scholar]
- Butzler J. P., Skirrow M. B. Campylobacter enteritis. Clin Gastroenterol. 1979 Sep;8(3):737–765. [PubMed] [Google Scholar]
- Cubitt W. D., Holzel H. An outbreak of rotavirus infection in a long-stay ward of a geriatric hospital. J Clin Pathol. 1980 Mar;33(3):306–308. doi: 10.1136/jcp.33.3.306. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Foster S. O., Palmer E. L., Gary G. W., Jr, Martin M. L., Herrmann K. L., Beasley P., Sampson J. Gastroenteritis due to rotavirus in an isolated Pacific island group: an epidemic of 3,439 cases. J Infect Dis. 1980 Jan;141(1):32–39. doi: 10.1093/infdis/141.1.32. [DOI] [PubMed] [Google Scholar]
- Greenberg H. B., Wyatt R. G., Valdesuso J., Kalica A. R., London W. T., Chanock R. M., Kapikian A. Z. Solid-phase microtiter radioimmunoassay for detection of the Norwalk strain of acute nonbacterial, epidemic gastroenteritis virus and its antibodies. J Med Virol. 1978;2(2):97–108. doi: 10.1002/jmv.1890020204. [DOI] [PubMed] [Google Scholar]
- Kaplan J. E., Gary G. W., Baron R. C., Singh N., Schonberger L. B., Feldman R., Greenberg H. B. Epidemiology of Norwalk gastroenteritis and the role of Norwalk virus in outbreaks of acute nonbacterial gastroenteritis. Ann Intern Med. 1982 Jun;96(6 Pt 1):756–761. doi: 10.7326/0003-4819-96-6-756. [DOI] [PubMed] [Google Scholar]
- Linhares A. C., Pinheiro F. P., Freitas R. B., Gabbay Y. B., Shirley J. A., Beards G. M. An outbreak of rotavirus diarrhea among a nonimmune, isolated South American Indian community. Am J Epidemiol. 1981 Jun;113(6):703–710. doi: 10.1093/oxfordjournals.aje.a113151. [DOI] [PubMed] [Google Scholar]
- Merson M. H., Morris G. K., Sack D. A., Wells J. G., Feeley J. C., Sack R. B., Creech W. B., Kapikian A. Z., Gangarosa E. J. Travelers' diarrhea in Mexico. A prospective study of physicians and family members attending a congress. N Engl J Med. 1976 Jun 10;294(24):1299–1305. doi: 10.1056/NEJM197606102942401. [DOI] [PubMed] [Google Scholar]
- Meurman O. H., Laine M. J. Rotavirus epidemic in adults. N Engl J Med. 1977 Jun 2;296(22):1298–1299. doi: 10.1056/NEJM197706022962220. [DOI] [PubMed] [Google Scholar]
- von Bonsdorff C. H., Hovi T., Mäkelä P., Mörttinen A. Rotavirus infections in adults in association with acute gastroenteritis. J Med Virol. 1978;2(1):21–28. doi: 10.1002/jmv.1890020105. [DOI] [PubMed] [Google Scholar]