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. 1995 Apr;5(2):123–129. doi: 10.1055/s-2008-1058943

Head and Neck Squamous Cell Carcinoma Metastatic to the Orbital Apex

Terry A Day, Denis K Hoasjoe, Richard L Hebert, Enrique Gonzalez, William Shockley, Fred J Stucker, Anil Nanda
PMCID: PMC1661818  PMID: 17171186

Abstract

Primary squamous cell carcinoma of the head and neck most commonly metastasizes to the lymph nodes, lung, bone, and liver. Many other rare sites of metastatic disease have been reported. To date, metastatic squamous cell carcinoma of the head and neck to the orbital apex has not been described. Presented are two cases, one tonsil and one parotid primary with metastatic disease to the orbital apex. Many tumors have been found to metastasize to the eye and orbit, but head and neck neoplasms are rarely reported. A review of the literature is presented in addition to the detailed case reports with their radiologic findings and clinical course. Surgical resection followed by postoperative radiotherapy appears the treatment of choice at this time.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERKE R. N. A modified Krönlein operation. Trans Am Ophthalmol Soc. 1953;51:193–231. [PMC free article] [PubMed] [Google Scholar]
  2. Conley J. The risk to the orbit in head and neck cancer. Laryngoscope. 1985 May;95(5):515–522. doi: 10.1288/00005537-198505000-00002. [DOI] [PubMed] [Google Scholar]
  3. Ferry A. P., Font R. L. Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases. Arch Ophthalmol. 1974 Oct;92(4):276–286. doi: 10.1001/archopht.1974.01010010286003. [DOI] [PubMed] [Google Scholar]
  4. Ferry A. P., Font R. L. Carcinoma metastatic to the orbit. Mod Probl Ophthalmol. 1975;14:377–381. [PubMed] [Google Scholar]
  5. Font R. L., Ferry A. P. Carcinoma metastatic to the eye and orbit III. A clinicopathologic study of 28 cases metastatic to the orbit. Cancer. 1976 Sep;38(3):1326–1335. doi: 10.1002/1097-0142(197609)38:3<1326::aid-cncr2820380336>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  6. Jensen O. A. Metastatic tumours of the eye and orbit. A histopathological analysis of a Danish series. Acta Pathol Microbiol Scand Suppl. 1970;212(Suppl):201+–201+. [PubMed] [Google Scholar]
  7. Kaplan M. J., Jane J. A., Park T. S., Cantrell R. W. Supraorbital rim approach to the anterior skull base. Laryngoscope. 1984 Sep;94(9):1137–1139. [PubMed] [Google Scholar]
  8. Kotwall C., Sako K., Razack M. S., Rao U., Bakamjian V., Shedd D. P. Metastatic patterns in squamous cell cancer of the head and neck. Am J Surg. 1987 Oct;154(4):439–442. doi: 10.1016/0002-9610(89)90020-2. [DOI] [PubMed] [Google Scholar]
  9. Leone C. R., Jr, Wissinger J. P. Surgical approaches to diseases of the orbital apex. Ophthalmology. 1988 Mar;95(3):391–397. doi: 10.1016/s0161-6420(88)33174-x. [DOI] [PubMed] [Google Scholar]
  10. Maroon J. C., Kennerdel J. S. Lateral microsurgical approach to intraorbital tumors. J Neurosurg. 1976 May;44(5):556–561. doi: 10.3171/jns.1976.44.5.0556. [DOI] [PubMed] [Google Scholar]
  11. Maroon J. C., Kennerdell J. S. Surgical approaches to the orbit. Indications and techniques. J Neurosurg. 1984 Jun;60(6):1226–1235. doi: 10.3171/jns.1984.60.6.1226. [DOI] [PubMed] [Google Scholar]
  12. Osguthorpe J. D., Saunders R. A., Adkins W. Y. Evaluation of and access to posterior orbital tumors. Laryngoscope. 1983 Jun;93(6):766–771. doi: 10.1288/00005537-198306000-00013. [DOI] [PubMed] [Google Scholar]
  13. Osguthorpe J. D. Surgical access to primary orbital tumors. Otolaryngol Clin North Am. 1988 Feb;21(1):135–153. [PubMed] [Google Scholar]
  14. Shields J. A., Bakewell B., Augsburger J. J., Flanagan J. C. Classification and incidence of space-occupying lesions of the orbit. A survey of 645 biopsies. Arch Ophthalmol. 1984 Nov;102(11):1606–1611. doi: 10.1001/archopht.1984.01040031296011. [DOI] [PubMed] [Google Scholar]
  15. Tijl J., Koornneef L., Eijpe A., Thomas L., Gonzalez D. G., Veenhof C. Metastatic tumors to the orbit--management and prognosis. Graefes Arch Clin Exp Ophthalmol. 1992;230(6):527–530. doi: 10.1007/BF00181773. [DOI] [PubMed] [Google Scholar]
  16. Wright J., Morgan G. Squamous cell carcinoma developing in an orbital cyst. Arch Ophthalmol. 1977 Apr;95(4):635–637. doi: 10.1001/archopht.1977.04450040101014. [DOI] [PubMed] [Google Scholar]

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