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. 1990 Mar 3;300(6724):566–569. doi: 10.1136/bmj.300.6724.566

Coffee consumption and death from coronary heart disease in middle aged Norwegian men and women.

A Tverdal 1, I Stensvold 1, K Solvoll 1, O P Foss 1, P Lund-Larsen 1, K Bjartveit 1
PMCID: PMC1662349  PMID: 2108750

Abstract

OBJECTIVE--To study the association between number of cups of coffee consumed per day and coronary death when taking other major coronary risk factors into account. DESIGN--Men and women attending screening and followed up for a mean of 6.4 years. SETTING--Cardiovascular survey performed by ambulatory teams from the National Health Screening Service in Norway. PARTICIPANTS--All middle aged people in three counties: 19,398 men and 19,166 women aged 35-54 years who reported neither cardiovascular disease or diabetes nor symptoms of angina pectoris or intermittent claudication. MAIN OUTCOME MEASURE--Predictive value of number of cups of coffee consumed per day. RESULTS--At initial screening total serum cholesterol concentration, high density lipoprotein cholesterol concentration, blood pressure, height, and weight were measured and self reported information about smoking history, physical activity, and coffee drinking habits was recorded. Altogether 168 men and 16 women died of coronary heart disease during follow up. Mean cholesterol concentrations for men and women were almost identical and increased from the lowest to highest coffee consumption group (13.1% and 10.9% respectively). With the proportional hazards model and adjustment for age, total serum and high density lipoprotein cholesterol concentrations, systolic blood pressure, and number of cigarettes per day the coefficient for coffee corresponded to a relative risk between nine or more cups of coffee and less than one cup of 2.2 (95% confidence interval 1.1 to 4.5) for men and 5.1 (0.4 to 60.3) for women. For men the relative risk varied among the three counties. CONCLUSIONS--Coffee may affect mortality from coronary heart disease over and above its effect in raising cholesterol concentrations.

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Selected References

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  1. Berry G. The analysis of mortality by the subject-years method. Biometrics. 1983 Mar;39(1):173–184. [PubMed] [Google Scholar]
  2. Bjartveit K., Foss O. P., Gjervig T., Lund-Larsen P. G. The cardiovascular disease study in Norwegian counties. Background and organization. Acta Med Scand Suppl. 1979;634:1–70. [PubMed] [Google Scholar]
  3. Bønaa K., Arnesen E., Thelle D. S., Førde O. H. Coffee and cholesterol: is it all in the brewing? The Tromsø Study. BMJ. 1988 Oct 29;297(6656):1103–1104. doi: 10.1136/bmj.297.6656.1103. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. LaCroix A. Z., Mead L. A., Liang K. Y., Thomas C. B., Pearson T. A. Coffee consumption and the incidence of coronary heart disease. N Engl J Med. 1986 Oct 16;315(16):977–982. doi: 10.1056/NEJM198610163151601. [DOI] [PubMed] [Google Scholar]
  5. LeGrady D., Dyer A. R., Shekelle R. B., Stamler J., Liu K., Paul O., Lepper M., Shryock A. M. Coffee consumption and mortality in the Chicago Western Electric Company Study. Am J Epidemiol. 1987 Nov;126(5):803–812. doi: 10.1093/oxfordjournals.aje.a114717. [DOI] [PubMed] [Google Scholar]
  6. Periti M., Salvaggio A., Quaglia G., Di Marzio L. Coffee consumption and blood pressure: an Italian study. Clin Sci (Lond) 1987 Apr;72(4):443–447. doi: 10.1042/cs0720443. [DOI] [PubMed] [Google Scholar]
  7. Solvoll K., Selmer R., Løken E. B., Foss O. P., Trygg K. Coffee, dietary habits, and serum cholesterol among men and women 35-49 years of age. Am J Epidemiol. 1989 Jun;129(6):1277–1288. doi: 10.1093/oxfordjournals.aje.a115247. [DOI] [PubMed] [Google Scholar]
  8. Stensvold I., Tverdal A., Foss O. P. The effect of coffee on blood lipids and blood pressure. Results from a Norwegian cross-sectional study, men and women, 40-42 years. J Clin Epidemiol. 1989;42(9):877–884. doi: 10.1016/0895-4356(89)90101-7. [DOI] [PubMed] [Google Scholar]
  9. Thelle D. S., Førde O. H., Arnesen E. Distribution of high-density lipoprotein cholesterol according to age, sex, and ethnic origin: cardiovascular disease study in Finnmark 1977. J Epidemiol Community Health. 1982 Dec;36(4):243–247. doi: 10.1136/jech.36.4.243. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Thelle D. S., Heyden S., Fodor J. G. Coffee and cholesterol in epidemiological and experimental studies. Atherosclerosis. 1987 Oct;67(2-3):97–103. doi: 10.1016/0021-9150(87)90270-x. [DOI] [PubMed] [Google Scholar]
  11. Tretli S., Bjartveit K., Foss O. P., Haider T., Lund-Larsen P. G. Intervention on cardiovascular disease risk factors in Finnmark county: changes after a period of three years. The Cardiovascular Disease Study in Finnmark County, Norway. Scand J Soc Med. 1985;13(1):1–13. doi: 10.1177/140349488501300101. [DOI] [PubMed] [Google Scholar]
  12. Tverdal A., Stensvold I., Solvoll K., Foss O. P., Lund-Larsen P., Bjartveit K. Coffee consumption and death from coronary heart disease in middle aged Norwegian men and women. BMJ. 1990 Mar 3;300(6724):566–569. doi: 10.1136/bmj.300.6724.566. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Tverdal A. Systolic and diastolic blood pressures as predictors of coronary heart disease in middle aged Norwegian men. Br Med J (Clin Res Ed) 1987 Mar 14;294(6573):671–673. doi: 10.1136/bmj.294.6573.671. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Vandongen R. Coffee and heart disease: the hypothesis re-examined. Med J Aust. 1988 Feb 15;148(4):161–162. [PubMed] [Google Scholar]
  15. Williams P. T., Wood P. D., Vranizan K. M., Albers J. J., Garay S. C., Taylor C. B. Coffee intake and elevated cholesterol and apolipoprotein B levels in men. JAMA. 1985 Mar 8;253(10):1407–1411. [PMC free article] [PubMed] [Google Scholar]

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