Skip to main content
The BMJ logoLink to The BMJ
. 1990 Sep 15;301(6751):513–515. doi: 10.1136/bmj.301.6751.513

Early detection of gastric cancer.

M T Hallissey 1, W H Allum 1, A J Jewkes 1, D J Ellis 1, J W Fielding 1
PMCID: PMC1663798  PMID: 2207416

Abstract

OBJECTIVE--To see whether investigation of dyspeptic patients aged over 40 after their first consultation with the general practitioner would increase the proportions with early and operable gastric cancers. DESIGN--Prospective study of gastric cancer in dyspeptic patients aged over 40 from a defined population. SETTING--10 General practices (six in central Birmingham, four in Sandwell); the Queen Elizabeth Hospital, Birmingham; and Sandwell District General Hospital. PATIENTS--2659 Patients aged 40 or over referred with dyspepsia. MAIN OUTCOME MEASURE--Increase in early and operable gastric cancers detected in middle aged patients with dyspepsia. RESULTS--Disease was identified in 1992 patients (75%). Fifty seven were found to have gastric cancer, 36 being treated by potentially curative resection, including 15 with early cancer. CONCLUSIONS--The investigation of dyspeptic patients over 40 at first attendance can increase the proportion of early gastric cancers detected to 26% and the proportion of operable cases to 63%. Such a policy has the potential to reduce mortality from gastric cancer in the population.

Full text

PDF
513

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allum W. H., Hallissey M. T., Dorrell A., Low J., Fielding J. W. Programme for early detection of gastric cancer. Br Med J (Clin Res Ed) 1986 Aug 30;293(6546):541–541. doi: 10.1136/bmj.293.6546.541. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Allum W. H., Hallissey M. T., Kelly K. A. Adjuvant chemotherapy in operable gastric cancer. 5 year follow-up of first British Stomach Cancer Group trial. Lancet. 1989 Mar 18;1(8638):571–574. doi: 10.1016/s0140-6736(89)91607-3. [DOI] [PubMed] [Google Scholar]
  3. Allum W. H., Powell D. J., McConkey C. C., Fielding J. W. Gastric cancer: a 25-year review. Br J Surg. 1989 Jun;76(6):535–540. doi: 10.1002/bjs.1800760604. [DOI] [PubMed] [Google Scholar]
  4. Davenport P. M., Morgan A. G., Darnborough A., De Dombal F. T. Can preliminary screening of dyspeptic patients allow more effective use of investigational techniques? Br Med J (Clin Res Ed) 1985 Jan 19;290(6463):217–220. doi: 10.1136/bmj.290.6463.217. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gear M. W., Ormiston M. C., Barnes R. J., Rocyn-Jones J., Voss G. C. Endoscopic studies of dyspepsia in the community: an "open-access" service. Br Med J. 1980 May 3;280(6223):1135–1135. doi: 10.1136/bmj.280.6223.1135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Harju E. Gastric polyposis and malignancy. Br J Surg. 1986 Jul;73(7):532–533. doi: 10.1002/bjs.1800730705. [DOI] [PubMed] [Google Scholar]
  7. Hisamichi S., Nozaki K., Kitagawa M., Mochizuki F., Gomi T. Evaluation of mass screening program for stomach cancer. Tohoku J Exp Med. 1976;118 (Suppl):69–77. doi: 10.1620/tjem.118.suppl_69. [DOI] [PubMed] [Google Scholar]
  8. Hisamichi S., Sugawara N. Mass screening for gastric cancer by X-ray examination. Jpn J Clin Oncol. 1984 Jun;14(2):211–223. [PubMed] [Google Scholar]
  9. Holdstock G., Bruce S. Endoscopy and gastric cancer. Gut. 1981 Aug;22(8):673–676. doi: 10.1136/gut.22.8.673. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. MORSON B. C. Carcinoma arising from areas of intestinal metaplasia in the gastric mucosa. Br J Cancer. 1955 Sep;9(3):377–385. doi: 10.1038/bjc.1955.36. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. MORSON B. C. Intestinal metaplasia of the gastric mucosa. Br J Cancer. 1955 Sep;9(3):365–376. doi: 10.1038/bjc.1955.35. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Mann J., Holdstock G., Harman M., Machin D., Loehry C. A. Scoring system to improve cost effectiveness of open access endoscopy. Br Med J (Clin Res Ed) 1983 Oct 1;287(6397):937–940. doi: 10.1136/bmj.287.6397.937. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Morson B. C., Sobin L. H., Grundmann E., Johansen A., Nagayo T., Serck-Hanssen A. Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol. 1980 Aug;33(8):711–721. doi: 10.1136/jcp.33.8.711. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Murakami T. Early cancer of the stomach. World J Surg. 1979 Nov;3(6):685–692. doi: 10.1007/BF01654788. [DOI] [PubMed] [Google Scholar]
  15. SWYNNERTON B. F., TRUELOVE S. C. Carcinoma of the stomach. Br Med J. 1952 Feb 9;1(4753):287–292. doi: 10.1136/bmj.1.4753.287. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Siurala M., Varis K., Wiljasalo M. Studies of patients with atrophic gastritis: a 10-15-year follow-up. Scand J Gastroenterol. 1966;1(1):40–48. doi: 10.1080/00365521.1966.11800612. [DOI] [PubMed] [Google Scholar]
  17. The flight from science. Br Med J. 1980 Jan 5;280(6206):1–2. [PMC free article] [PubMed] [Google Scholar]
  18. Walker I. R., Strickland R. G., Ungar B., Mackay I. R. Simple atrophic gastritis and gastric carcinoma. Gut. 1971 Nov;12(11):906–911. doi: 10.1136/gut.12.11.906. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from BMJ : British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES