Correction

NEUROSCIENCE. For the article “Positive and negative regulation of APP amyloidogenesis by sumoylation,” by Yonghong Li, Hui Wang, Su Wang, Diana Quon, Yu-Wang Liu, and Barbara Cordell, which appeared in issue 1, January 7, 2003, of Proc. Natl. Acad. Sci. USA (100, 259–264; First Published December 27, 2002; 10.1073/pnas.0235361100), the authors note that they inadvertently labeled the 95-aa ubiquitin-like protein, which was identified from the library screen (see the first paragraph of Results), as SUMO-3 instead of SUMO-2. SUMO-2 and SUMO-3 are 95% identical at amino acid levels and are considered as a subfamily SUMO-2/3. The antibody used was raised against full-length SUMO-3 but recognizes SUMO-2 as well. The error does not affect the interpretations and conclusions of the paper except that all statements regarding effect of SUMO-3 should be viewed as that of SUMO-2.