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. 1972 Jan;44(1):31–44. doi: 10.1111/j.1476-5381.1972.tb07235.x

Pharmacological properties of amino-oxyacetic acid in the chicken

G Osuide
PMCID: PMC1665684  PMID: 5015039

Abstract

1. The effects of amino-oxyacetic acid (AOAA) on the central nervous system and on skeletal muscle have been examined in the chicken.

2. AOAA had both anticonvulsant and convulsant effects, depending on the dose, as in other species.

3. The convulsant effect, accompanied by EEG spiking, decreased rapidly with increase in age of young chicks.

4. The convulsant effect was exerted primarily through supraspinal centres.

5. Of control depressants tested, only troxidone and small doses of AOAA afforded significant protection against AOAA seizures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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