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. 1972 Feb;44(2):307–310. doi: 10.1111/j.1476-5381.1972.tb07268.x

Catecholamine concentrations and the activity of tyrosine hydroxylase after an increase in the concentration of tyrosine in rat tissues

W Dairman
PMCID: PMC1666031  PMID: 4148919

Abstract

The concentrations of tyrosine in rat plasma and brain were increased 2-7 fold by the administration of either L-tyrosine or cycloheximide. Under these conditions catecholamine concentrations in the brain and the heart remained unchanged even when the rats were maintained in a cold environment to increase catecholamine turnover. The data are interpreted to mean that an increase in the tyrosine concentration in the tissues does not result in an in vivo substrate inhibition of tyrosine hydroxylase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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