Abstract
The effect of propranolol, a β-adrenoceptor blocking agent, has been investigated on gastric acid secretion in pylorus and cardiac-ligated rats. Compared to the control group, propranolol significantly diminished the gastric acid secretion, and inhibited the formation of gastric ulceration.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Anshelevich Iu V. Potentsirovanie beta-adrenolitikami deistviia atropina na bazal'nuiu sekretsiiu zheludka u bol'nykh iazvoi dvanadtsatiperstnoi kishki. Ter Arkh. 1969 Nov;41(11):80–82. [PubMed] [Google Scholar]
- Bass P., Patterson M. A. Gastric secretory responses to drugs affecting adrenergic mechanisms in rats. J Pharmacol Exp Ther. 1967 Apr;156(1):142–149. [PubMed] [Google Scholar]
- Geumei A., Issa I., el-Gendi M., Abd-el-Samie Y. Inhibitory effect of beta-adrenergic-blocking agent propranolol on histamine-stimulated gastric acid secretion in man. Am J Dig Dis. 1972 Jan;17(1):55–58. doi: 10.1007/BF02239261. [DOI] [PubMed] [Google Scholar]
- Geumei A., Issa I., el-Gindi M., Abd-El-Samie Y. Beta-adrenergic receptors and gastric acid secretion. Surgery. 1969 Oct;66(4):663–668. [PubMed] [Google Scholar]
- Konturek S. J., Oleksy J. The effect of cholinergic and adrenergic blockage on basal and pentagastrin-induced acid secretion. Scand J Gastroenterol. 1969;4(1):13–16. doi: 10.3109/00365526909180145. [DOI] [PubMed] [Google Scholar]
- Misher A., Pendleton R. G., Staples R. Effects of adrenergic drugs upon gastric secretion in rats. Gastroenterology. 1969 Sep;57(3):294–299. [PubMed] [Google Scholar]
- Okabe S., Saziki R., Takagi K. Effects of adrenergic blocking agents on gastric secretion and stress-induced gastric ulcer in rats. Jpn J Pharmacol. 1970 Mar;20(1):10–15. doi: 10.1254/jjp.20.10. [DOI] [PubMed] [Google Scholar]
- Pradhan S. N., Wingate H. W. Effects of some adrenergic blocking agents on gastric secretion in dogs. Arch Int Pharmacodyn Ther. 1966 Aug;162(2):303–310. [PubMed] [Google Scholar]
- Rosoff C. B., Goldman H. Effect of the intestinal bacterial flora on acute gastric stress ulceration. Gastroenterology. 1968 Aug;55(2):212–222. [PubMed] [Google Scholar]
- SKORYNA S. C., WEBSTER D. R. A method of collection of pure gastric secretion in rats. Surg Forum. 1960;10:193–196. [PubMed] [Google Scholar]