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. 1975 Apr;53(4):598–599. doi: 10.1111/j.1476-5381.1975.tb07401.x

Effect of tetramethylenedisulphotetramine on the membrane conductance increase produced by gamma-amino-butyric acid at the crab neuromuscular junction.

W A Large
PMCID: PMC1666319  PMID: 1148503

Abstract

The effect of tetramethylenedisulphotetramine (TETS) on the increase in membrane conductance produced by gamma-aminobutyric acid (GABA) at the hermit crab neuromuscular junction was investigated. TETS produced a dose-dependent antagonism of GABA, which was characterized by a non-parallel shift of the log dose-conductance curve for GABA with a reduced maximal conductance change.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bowery N. G., Brown D. A., Collins J. F. Tetramethylenedisulphotetramine: an inhibitor of gamma-aminobutyric acid induced depolarization of the isolated superior cervical ganglion of the rat. Br J Pharmacol. 1975 Mar;53(3):422–424. doi: 10.1111/j.1476-5381.1975.tb07379.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bowery N. G., Brown D. A. Depolarizing actions of gamma-aminobutyric acid and related compounds on rat superior cervical ganglia in vitro. Br J Pharmacol. 1974 Feb;50(2):205–218. doi: 10.1111/j.1476-5381.1974.tb08563.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Earl J., Large W. A. Electrophysiological investigation of GABA-mediated inhibition at the hermit crab neuromuscular junction. J Physiol. 1974 Jan;236(1):113–127. doi: 10.1113/jphysiol.1974.sp010425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gerschenfeld H. M. Chemical transmission in invertebrate central nervous systems and neuromuscular junctions. Physiol Rev. 1973 Jan;53(1):1–119. doi: 10.1152/physrev.1973.53.1.1. [DOI] [PubMed] [Google Scholar]

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