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. 1972 Oct;46(2):351–354. doi: 10.1111/j.1476-5381.1972.tb06881.x

The effect of betahistine on gastric acid secretion and mucosal blood flow in conscious dogs

B P Curwain, Pamela Holton, Jan Spencer
PMCID: PMC1666342  PMID: 4631339

Abstract

In 3 conscious dogs, betahistine (2-(2'-methyl aminoethyl pyridine)) (80 or 160μg kg-1 min-1) increased acid secretion from Heidenhain pouches to 8·8% and 17·6% respectively of the maximal response to histamine. Betahistine also increased mucosal blood flow (radioactive aniline clearance). The ratio of mucosal blood flow to secretion was greater for betahistine than for histamine but the difference between betahistine and histamine was significant in only one of the dogs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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