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. 1972 Nov;46(3):508–510. doi: 10.1111/j.1476-5381.1972.tb08148.x

Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension

K M Dhasmana, W A B Fokker, B A Spilker
PMCID: PMC1666500  PMID: 4511871

Abstract

A method for stimulating discrete segments of the spinal autonomic outflow in the pithed rat was found suitable for differentiating between the group of centrally acting antihypertensive agents α-methyldopa, clonidine and iproniazid and other antihypertensive compounds which additionally have peripheral vascular effects mediated via the peripheral sympathetic nerves.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gillespie J. S., Maclaren A., Pollock D. A method of stimulating different segments of the autonomic outflow from the spinal column to various organs in the pithed cat and rat. Br J Pharmacol. 1970 Oct;40(2):257–267. doi: 10.1111/j.1476-5381.1970.tb09919.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
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