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. 1977 Feb;59(2):349–351. doi: 10.1111/j.1476-5381.1977.tb07499.x

Nature of histamine receptors concerned in capillary permeability.

K P Bhargava, R Nath, G Palit
PMCID: PMC1667728  PMID: 837022

Abstract

1 Histamine and 2-methyl-histamine (H1-receptor agonist) caused dose-dependent increases in capillary permeability in albino mice, but 4-methyl-histamine (H2-receptor agonist) caused no significant increase. 2 Mepyramine (H1-receptor antagonist) blocked the histamine-induced increase in capillary permeability whereas burimamide (H2-receptor antagonist) produced no significant blockade of the histamine-response. 3 Combined mepyramine and burimamide pretreatment did not give any significantly greater protection than mepyramine alone. 4 The results indicate involvement of the H1-receptors in histamine-induced increase in capillary permeability.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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